Can a chemo drug keep sarcoma at bay? new trial aims to find out

NCT ID NCT06981637

First seen Jun 25, 2026 · Last updated Jun 27, 2026 · Updated 1 time

Summary

This Phase 2 trial tests whether a chemotherapy drug called pegylated liposomal doxorubicin (PLD) can help people with advanced soft tissue sarcoma live longer without their cancer growing. Participants who have already responded to standard chemotherapy will either receive PLD every 4 weeks for up to 12 cycles or be closely monitored without treatment. The study aims to see if maintenance therapy delays cancer progression compared to active surveillance.

What this could mean

Our plain-language read of the trial. This is informational only — not medical advice or a prediction.

Active substance

Pegylated liposomal doxorubicin (a chemotherapy drug)

What this could lead to

If successful, this could provide a new maintenance option to delay cancer progression in advanced soft tissue sarcoma patients who have already responded to initial chemotherapy.

What could go wrong

This is a small Phase 2 trial with only 81 participants, so results may not be conclusive. The drug can cause side effects like heart damage or low blood counts, and it may not improve survival.

Disclaimer Read more

This is a summary of the original study . Summaries may miss details or leave out important information. Before applying or accepting participation, make sure you have read and understood the full study. Curemydisease.com takes no responsibility whatsoever for anything missed, misunderstood, or acted upon as a result of our summary — we know it does not capture everything.

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Conditions

The condition(s) this trial relates to.

soft tissue sarcoma

As listed by the trial registrant

The condition terms exactly as the trial's registrant entered them.

Contacts and locations

Study contacts

  • Contact

    Phone: •••-•••-•••• Email: •••••@•••••

  • Contact

    Phone: •••-•••-•••• Email: •••••@•••••

Locations

  • Chang Gung Memorial Hospital

    NOT_YET_RECRUITING

    Kaohsiung City, Taiwan

    Contact

  • China Medical University Hospital

    RECRUITING

    Taichung, Taiwan

    Contact

  • Kaohsiung Medical University Chung-Ho Memorial Hospital,

    RECRUITING

    Kaohsiung City, Taiwan

    Contact

  • National Cheng Kung University Hospital

    RECRUITING

    Tainan, Taiwan

    Contact

  • National Taiwan University Hospital

    RECRUITING

    Taipei, Taiwan

    Contact Email: •••••@•••••

  • Taipei Veterans General Hospital

    RECRUITING

    Taipei, Taiwan

    Contact

  • Tri-Service General Hospital

    RECRUITING

    Taipei, Taiwan

    Contact