Can diet, exercise, and pills tame metabolic syndrome?
NCT ID NCT06271200
First seen Jun 24, 2026 · Last updated Jun 27, 2026 · Updated 1 time
Summary
This study tests whether a strict lifestyle program—eating only during an 8-hour window, walking 10,000 steps daily, and cutting 500 calories—can help obese adults with metabolic syndrome lose weight and improve heart health. After 24 weeks, participants also receive either Rybelsus or Forxiga, two weight-loss medications, for another 26 weeks. The goal is to see if these approaches work together to reduce metabolic risks and sustain weight loss over a year.
What this could mean
Our plain-language read of the trial. This is informational only — not medical advice or a prediction.
- Active substance
- lifestyle intervention (time-restricted eating, walking, calorie reduction) and weight-loss medications (Rybelsus or Forxiga)
- What this could lead to
- If successful, this could show that combining lifestyle changes with medication helps obese adults with metabolic syndrome lose weight and reduce heart disease risk.
- What could go wrong
- This is a mid-stage trial with 200 participants, so results may not apply to everyone. The lifestyle program is demanding, and medications can have side effects like nausea or dehydration.
This is an AI summary of the original study and may miss details. Read our disclaimer.
Get updates
Get notified about this study
Sign up to get updates when this study changes or when new studies for METABOLIC SYNDROME are added.
By submitting, you agree to our Terms of use
Conditions
The condition(s) this trial relates to.
As listed by the trial registrant
The condition terms exactly as the trial's registrant entered them.
Contacts and locations
Locations
-
Institute of Molecular and Genomic Medicine, National Health Resesarch Institutes
RECRUITINGZhunan, Miaoli County, 350, Taiwan
More trials for these conditions
Other studies related to the condition(s) this trial covers.
- Seaweed extract may tackle fatty liver Disease—A trial puts it to the test
- Ancient herb huangjing put to the test against hidden belly fat
- Lifestyle overhaul may restore penile blood flow in metabolic syndrome
- Can a Plant-Based protein switch reshape your metabolism?
- Plant protein drink may shield aging Hearts—A trial puts it to the test
- Could a simple diet beat metabolic syndrome? genes may hold the key