National Eye Institute (nei)

This study tested whether the oral antibiotic minocycline could safely slow the progression of geographic atrophy, an advanced and untreatable form of dry age-related macular degeneration that causes central vision loss. Participants aged 55+ with the condition took minocycline p…

This study aimed to find the best eye tests for tracking vision loss in people with retinitis pigmentosa (RP), a group of blinding eye diseases. Researchers tested 49 participants, including people with RP and healthy volunteers, with multiple eye exams repeated about six weeks a…

This study aimed to understand if factors during a mother's first three months of pregnancy might contribute to a child being born with an eye defect called coloboma. Researchers surveyed 76 mothers of children with coloboma, asking about their health, medicine use, and exposures…

This study aimed to build a long-term collection of health information and biological samples from people with uveitis, a serious inflammatory eye disease. Over 10 years, researchers followed 343 participants to gather data and samples like blood and tears. The goal was to discov…

This study aimed to build a national DNA and blood sample bank from people with inherited eye diseases, like retinitis pigmentosa. Over 6,600 participants provided samples and eye exam information to help researchers identify the genetic causes of these conditions. The repository…

This study aimed to better understand how early age-related macular degeneration (AMD) changes over time. Researchers followed about 500 adults aged 55 and older, some with early AMD, some with a specific type called RPD, and some with healthy eyes, for up to 5 years. They regula…

This study aimed to better understand how geographic atrophy, an advanced form of age-related macular degeneration, naturally progresses over time. It observed 20 adults aged 55 and older with this condition for nearly four years, tracking changes in their eyes through regular ex…

This study aimed to understand if the natural bacteria in a person's gut are related to uveitis, a group of inflammatory eye diseases. Researchers compared stool and blood samples from 131 adults with uveitis to samples from healthy adults without the condition. The goal was to g…