National Eye Institute (nei)

This study tested whether the antibiotic minocycline, taken as a pill twice daily for three years, could safely slow the growth of geographic atrophy (an advanced form of dry age-related macular degeneration) and preserve vision. Thirty-seven adults aged 55 and older with geograp…

This study looked at the natural bacteria in the gut of 131 adults—some with uveitis (an inflammatory eye disease) and some healthy—to see if differences in gut microbes are linked to eye inflammation. Participants provided stool and blood samples and had eye exams, but no treatm…

This study looked at how well different eye exams can measure changes in retinitis pigmentosa (RP), a group of eye diseases that cause blindness. Researchers tested 49 people with RP and healthy volunteers using several vision tests, repeating them about six weeks later to see ho…

This study followed people aged 55 and older with early age-related macular degeneration (AMD) or a related condition called reticular pseudodrusen (RPD), along with healthy volunteers. Researchers used eye exams, imaging, and vision tests to track changes over up to 5 years. The…

This study collected blood, tissue, and other samples from 343 people with uveitis (a serious eye disease) to learn why some people get it and how they respond to treatment. Participants were followed for up to 10 years with eye exams and tests. The goal was to gather information…

This study created a national DNA and blood bank for inherited eye diseases like retinitis pigmentosa. Over 6,600 participants provided blood samples and had eye exams to help researchers identify genetic causes. The goal is to speed up research into new treatments for these rare…

This study investigates whether things a mother is exposed to during early pregnancy might cause uveal coloboma, a rare eye malformation present at birth. Researchers will survey 76 mothers of children with coloboma about their health, medications, and lifestyle during the first …

This study followed 20 adults aged 55 and older with geographic atrophy, an advanced form of age-related macular degeneration that causes central vision loss. Researchers measured how the damaged area in the eye changed over nearly 4 years using eye exams and photos. The goal was…