Could Mom's pregnancy exposures cause Baby's eye defect?

NCT ID NCT04833361

First seen Jun 26, 2026 · Last updated Jun 27, 2026 · Updated 1 time

Summary

This study explores whether things a mother is exposed to during early pregnancy might cause uveal coloboma, a rare eye condition present at birth. Researchers will survey mothers of affected children and compare their answers to historical data. The goal is to identify possible environmental risk factors for further study.

What this could mean

Our plain-language read of the trial. This is informational only — not medical advice or a prediction.

What this could lead to

If successful, this study could point toward environmental risk factors for coloboma, helping guide future prevention research.

What could go wrong

This is a small, early-stage pilot study using historical data and surveys, so it cannot prove cause and effect. Results may not lead to direct medical changes.

Disclaimer Read more

This is a summary of the original study . Summaries may miss details or leave out important information. Before applying or accepting participation, make sure you have read and understood the full study. Curemydisease.com takes no responsibility whatsoever for anything missed, misunderstood, or acted upon as a result of our summary — we know it does not capture everything.

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Conditions

The condition(s) this trial relates to.

coloboma Congenital Abnormalities microphthalmia

As listed by the trial registrant

The condition terms exactly as the trial's registrant entered them.

Contacts and locations

Locations

  • National Eye Institute (NEI)

    Bethesda, Maryland, 20892, United States