National Eye Institute (nei)

This study looks back at 20 years of medical records from 25 people who had a rare eye tumor called retinal hemangioblastoma treated with freezing therapy (cryotherapy). The goal is to see how well the treatment controls the tumor and prevents vision loss. No new participants are…

This study follows 57 people with age-related macular degeneration (AMD) for up to 5 years to see how their eyes adjust to darkness over time. Participants, who completed an earlier study, will have eye exams and dark adaptation tests at least 6 times. The goal is to better under…

This study follows 68 people aged 12 and older who have changes in the ABCA4 gene, which can cause vision loss. Over 10 years, researchers will track how the disease progresses using eye exams, blood tests, and skin samples. No treatment is given; the goal is to gather informatio…

This study is a 5-year extension that follows people who were in the original AREDS or AREDS2 studies. The goal is to observe how age-related macular degeneration (AMD) and cataracts naturally progress over time. Participants get a yearly eye exam and a phone check-in. No new tre…

This study follows 217 adults aged 50 and older with or without early to middle dry age-related macular degeneration (AMD) for up to 5 years. Researchers use a 20-40 minute dark adaptation test to measure how quickly eyes recover in low light. The goal is to see if this test can …

This study looks at X-linked juvenile retinoschisis, an inherited eye disease that causes vision loss mainly in young males. Researchers want to understand why and how the retina splits, leading to worsening sight over time. Participants include patients aged 9 months and older, …