National Eye Institute (nei)
Clinical trials sponsored by National Eye Institute (nei), explained in plain language.
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Could a common diabetes drug protect eyesight in stargardt disease?
Disease control OngoingThis study tests whether metformin, a widely used diabetes drug, can safely slow vision loss in people with ABCA4 retinopathy (Stargardt disease). Fifty-five participants aged 12 and older will take metformin by mouth for 24 months, with regular eye exams to track changes. The go…
Phase: PHASE1, PHASE2 • Sponsor: National Eye Institute (NEI) • Aim: Disease control
Last updated Aug 12, 2026 00:00 UTC
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New study tracks rare disease SCA7 to uncover clues for future treatments
Knowledge-focused OngoingThis study follows 25 people with spinocerebellar ataxia type 7 (SCA7) for up to 5 years to learn how the disease changes vision, coordination, and thinking. Participants will have yearly eye exams, brain scans, and neurological tests. No treatment is given; the goal is to gather…
Sponsor: National Eye Institute (NEI) • Aim: Knowledge-focused
Last updated Aug 15, 2026 00:00 UTC
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Scientists track rare eye disease to prepare for future treatments
Knowledge-focused OngoingThis study follows 68 people aged 12 and older who have ABCA4 gene mutations, which can cause vision loss from diseases like Stargardt disease. Over 10 years, researchers will collect blood and skin samples and perform detailed eye exams to understand how the disease progresses. …
Sponsor: National Eye Institute (NEI) • Aim: Knowledge-focused
Last updated Aug 09, 2026 00:00 UTC
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Scientists track eye disease progression over five years
Knowledge-focused OngoingThis study follows 110 people who previously took part in the AREDS or AREDS2 trials to see how age-related macular degeneration (AMD) and cataracts change over time. Participants get a yearly eye exam, including vision tests and eye photos, and may give a blood sample. The goal …
Sponsor: National Eye Institute (NEI) • Aim: Knowledge-focused
Last updated Jul 30, 2026 00:00 UTC