Diabetes drug metformin could slow blindness in rare eye disease

NCT ID NCT04545736

First seen Nov 01, 2025 · Last updated May 16, 2026 · Updated 21 times

Summary

This study tests whether the diabetes drug metformin is safe and can slow vision loss in people with ABCA4 retinopathy (Stargardt disease), a genetic condition that causes progressive blindness. About 56 participants aged 12 and older will take metformin daily for 24 months, with regular eye exams to measure changes. The goal is to see if metformin can reduce the rate of retinal damage.

Disclaimer Read more

This is a summary of the original study . Summaries may miss details or leave out important information. Before applying or accepting participation, make sure you have read and understood the full study. Curemydisease.com takes no responsibility whatsoever for anything missed, misunderstood, or acted upon as a result of our summary — we know it does not capture everything.

Get updates

Get notified about this study

Sign up to get updates when this study changes or when new studies for RETINAL DEGENERATION are added.

Our safety recommendation!

By submitting, you agree to our Terms of use

Contacts and locations

Study contacts

  • Contact

    Phone: •••-•••-•••• Email: •••••@•••••

  • Contact

    Phone: •••-•••-•••• Email: •••••@•••••

Locations

  • National Institutes of Health Clinical Center

    RECRUITING

    Bethesda, Maryland, 20892, United States

    Contact Phone: •••-•••-•••• Email: •••••@•••••

  • University of Michigan

    RECRUITING

    Ann Arbor, Michigan, 48109-0624, United States

    Contact Phone: •••-•••-•••• Email: •••••@•••••

Conditions

Explore the condition pages connected to this study.