Eye tests under the microscope for blinding disease

NCT ID NCT03845218

Completed Knowledge-focused Sponsor: National Eye Institute (NEI) Source: ClinicalTrials.gov ↗

First seen Jun 26, 2026 · Last updated Jun 27, 2026 · Updated 1 time

Summary

This completed study looked at how well different eye tests can track changes in retinitis pigmentosa (RP), a group of blinding eye diseases. Researchers tested 49 people with RP and healthy volunteers using exams like vision tests, retinal imaging, and electrical signal recordings. The goal was to find which tests are most reliable for measuring disease progression, which could help design better future treatment trials.

What this could mean

Our plain-language read of the trial. This is informational only — not medical advice or a prediction.

What this could lead to: If successful, this study could help design better clinical trials for retinitis pigmentosa treatments by identifying the most reliable tests.
What could go wrong: This was a small, observational study with no treatment tested. Results may not apply to all RP patients or lead directly to new therapies.

This is an AI summary of the original study and may miss details. Read our disclaimer.

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Conditions

The condition(s) this trial relates to.

retinitis pigmentosa

As listed by the trial registrant

The condition terms exactly as the trial's registrant entered them.

RETINITIS PIGMENTOSA

Contacts and locations

Locations

National Institutes of Health Clinical Center

Bethesda, Maryland, 20892, United States

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Other studies related to the condition(s) this trial covers.