Murdoch Childrens Research Institute

This study tests two different COVID-19 booster vaccines—Moderna's bivalent mRNA and Novavax's protein-based—in 496 healthy adults who have already had three doses. The goal is to see which booster produces a stronger immune response and causes fewer side effects. Participants wi…

This study compares two methods of giving breathing support (PEEP) to very premature babies right after birth. About 900 babies born between 23 and 28 weeks will be randomly assigned to receive either a steady PEEP level or a high-then-low approach. The goal is to see which metho…

This study tests whether giving vitamin D supplements to healthy, breastfed babies during their first year can prevent food allergies. Over 2,700 infants in Australia are participating. Researchers will check for food allergies at 12 months and again at 6 years old.

This study tests a 6-week group program called Working Out Dads (WOD) to see if it helps reduce mental health struggles in fathers of children aged 0-4. About 293 dads with mild to moderate distress will either join the WOD peer-support group or receive usual care. The goal is to…

This study looks at how well a single dose of ivermectin works in young children (3 months to under 5 years) with scabies. Researchers want to find the right dose that is both safe and effective for this age group. The study involves 120 children in Laos and is part of a larger n…

This study tests a new liquid version of the drug ivermectin, designed for infants, against the standard tablet. 52 healthy adults will try both forms to see if they work the same, taste okay, and are safe. The goal is to make treating scabies easier for babies.