Menoufia University

This trial investigates whether giving a blood thinner (enoxaparin) to critically ill children with a central venous line can reduce complications like clots and blockages. About 80 children in the pediatric ICU will be randomly assigned to receive either enoxaparin or standard c…

This trial tests whether plasma exchange (a blood-cleaning procedure) given every other day works as well as daily sessions for children with autoimmune encephalitis, a condition where the immune system attacks the brain. The study involves 22 children who are randomly assigned t…

This trial investigates whether therapeutic plasma exchange — a procedure that filters the blood to remove harmful substances — can reduce deaths in critically ill children with severe sepsis or septic shock. Participants are randomly assigned to receive either standard sepsis ca…

This study compares two surgical methods for removing large staghorn kidney stones: flexible ureteroscopy (FURS) and percutaneous nephrolithotomy (PCNL). PCNL is the standard but can cause serious complications; FURS is less invasive but may need multiple sessions. The trial will…

This study compares two positions—lying on your back (lithotomy) versus lying on your side (lateral)—during a minimally invasive surgery for kidney stones smaller than 2 cm. The goal is to see which position helps clear stones more completely. Seventy adults with lower calyx kidn…

This study tests whether combining an antibiotic (linezolid) with a mucus-dissolving agent can reduce the sticky bacterial film (biofilm) that forms on ureteral stents placed after kidney stone surgery. About 100 adults who are stone-free and have a stent for one month will be ra…

This study looks at whether measuring oxygen levels in a central vein can help doctors decide if a patient with septic shock needs more fluids. About 115 adults with septic shock will have their oxygen levels checked before and after a fluid challenge. The results will be compare…

This study tests whether using a virtual reality (VR) headset during hip replacement surgery can lower anxiety and prevent post-surgery confusion in older adults. Half of the participants will watch calming nature scenes through VR while under regional anesthesia, while the other…

This study compares three types of nerve blocks used for pain relief during shoulder surgery. The goal is to see which block is least likely to temporarily paralyze the diaphragm, the main muscle used for breathing. Seventy-five adults having shoulder surgery will be randomly ass…

This study looks at how the size of the connector piece (abutment) on a dental implant affects the bone around it. Researchers will place implants in 40 adults with a missing back tooth and use either a narrow or regular abutment. Over 24 months, they will measure bone changes on…