Blood filtering may save children with sepsis
NCT ID NCT07706413
First seen Jul 15, 2026 · Last updated Jul 16, 2026 · Updated 1 time
Summary
This trial investigates whether therapeutic plasma exchange — a procedure that filters the blood to remove harmful substances — can reduce deaths in critically ill children with severe sepsis or septic shock. Participants are randomly assigned to receive either standard sepsis care alone or standard care plus plasma exchange. The study measures survival, organ function, and recovery time in the pediatric intensive care unit.
What this could mean
Our plain-language read of the trial. This is informational only — not medical advice or a prediction.
- Active substance
- therapeutic plasma exchange (a procedure that filters the blood to remove harmful substances)
- What this could lead to
- If it works, this could offer a way to lower the risk of death and organ failure in children with severe sepsis.
- What could go wrong
- This is a small, early-stage trial, so results may not apply broadly. Plasma exchange carries risks like bleeding or infection from catheter placement.
This is an AI summary of the original study and may miss details. Read our disclaimer.
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Conditions
The condition(s) this trial relates to.
As listed by the trial registrant
The condition terms exactly as the trial's registrant entered them.
Contacts and locations
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Study contacts
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Contact
Phone: •••-•••-•••• Email: •••••@•••••
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Contact
Phone: •••-•••-•••• Email: •••••@•••••
Locations
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Menoufia university hospital, Pediatric intensive care unit
Shibīn al Kawm, Menoufia Governorate, Egypt
Contact
Contact Phone: •••-•••-•••• Email: •••••@•••••
Contact
Contact Phone: •••-•••-•••• Email: •••••@•••••
Contact
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