Can less be more? study tests cutting back antibiotics in sepsis

NCT ID NCT01626612

First seen May 12, 2026 · Last updated Jun 19, 2026 · Updated 11 times

Summary

This study looked at whether it is safe to reduce or narrow antibiotics once doctors know which germ is causing a severe infection (sepsis). 120 intensive care patients were randomly assigned to either continue their original broad antibiotics or switch to a more targeted treatment. The goal was to see if the de-escalation approach could keep patients safe while reducing the risk of drug-resistant infections.

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This is a summary of the original study . Summaries may miss details or leave out important information. Before applying or accepting participation, make sure you have read and understood the full study. Curemydisease.com takes no responsibility whatsoever for anything missed, misunderstood, or acted upon as a result of our summary — we know it does not capture everything.

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Contacts and locations

Locations

  • Assistance Publique Hopitaux de Marseille

    Marseille, 13354, France

Conditions

The condition(s) this trial relates to.

Sepsis

As listed by the trial registrant

The condition terms exactly as the trial's registrant entered them.