Melanoma Institute Australia

This study is testing if giving two targeted drugs (dabrafenib and trametinib) for 12 weeks before surgery can shrink melanoma tumors that have spread to the lymph nodes. It involves 35 adults with a specific genetic mutation (BRAF V600). The main goal is to see if this pre-surge…

This study is testing whether giving two drugs—pembrolizumab and lenvatinib—for six weeks before surgery can better control stage III melanoma. The goal is to shrink the tumor and boost the body's immune response to improve long-term results after the operation. It involves 21 ad…

This trial is testing whether giving a two-drug immunotherapy treatment before surgery can help people with high-risk Stage II melanoma. The goal is to shrink the tumor and reduce the chance of the cancer coming back after surgery. The study will enroll about 20 adults with thick…

This study is testing whether two immunotherapy drugs, nivolumab alone or nivolumab combined with ipilimumab, can help control melanoma that has spread to the brain. It enrolled 76 adults with these brain metastases. The goal is to see if these drugs, which help the immune system…