Melanoma Institute Australia

This phase II trial tests whether giving two targeted drugs (dabrafenib and trametinib) before and after surgery can improve outcomes for people with stage IIIB-C melanoma that has a BRAF V600 mutation. 35 participants will take the drugs for 12 weeks before surgery, then continu…

This study looked at 216 people with advanced melanoma that had stopped responding to standard treatments. Researchers tested each person's tumor for specific genetic changes and then gave them a drug designed to target that change. The goal was to see if this personalized approa…

This study tested whether taking a daily pill called sonidegib for 12 weeks could shrink basal cell carcinomas in cosmetically sensitive areas like the face. The goal was to make surgery less invasive, reduce scarring, or even avoid surgery altogether by using only a topical crea…