Mclean Hospital

This early-stage study is testing whether a dietary supplement called nicotinamide riboside (a form of vitamin B3) can improve brain cell energy and reduce harmful stress in people with mild memory problems or early Alzheimer's disease. Researchers will give the supplement to 50 …

This study aimed to see if a medication called lorcaserin could help people with cocaine dependence by rebalancing brain chemistry. Researchers planned to use brain scans to measure if the drug reduced reactions to drug cues and impulsive behavior. The study was withdrawn before …

This small, early-stage study is testing whether a liquid CBD solution placed under the tongue can help reduce anxiety and agitation in older adults with mild memory problems or early Alzheimer's disease. The 12 participants will take the solution for eight weeks while researcher…

This study aims to understand how a magnetic stimulation treatment affects the brain in older adults with bipolar depression. Researchers will use brain scans before and after treatment to measure changes in brain activity. The goal is to gather information that could help guide …

This study aimed to understand if a drug called LY-2940094 could protect healthy people from developing depression- and anxiety-like symptoms after stress. Researchers planned to give the drug to volunteers and then measure their brain's reward system and fear responses in a lab …

This study aims to understand how people who have recovered from major depression make decisions and which brain areas are involved. Researchers will use MRI brain scans and decision-making tasks to see if they can predict who might experience depression symptoms in the future. T…

This study aims to understand how childhood trauma affects the brain in women with PTSD or dissociative identity disorder. Researchers will use brain scans and genetic tests to look for patterns linked to dissociative symptoms. The study involves 200 women and includes follow-up …