Mclean Hospital

This study tested a smartphone app made just for women with opioid use disorder to help them stay on their medication treatment. 39 women who had recently started medication for opioid use disorder used the app along with their usual care. Researchers checked if women found the a…

This study tested a computer-based cognitive training program in 72 adults with bipolar disorder who also had psychosis. The goal was to see if the training could improve memory, attention, and problem-solving skills compared to a control computer activity. Participants were with…

This study looked at how well the McLean Anxiety Mastery Program helps children and teens aged 6 to 19 with anxiety disorders like social anxiety, panic, and phobias. Researchers collected surveys from 559 participants to see if symptoms improved from the start to the end of trea…

This study looked at 70 women with severe menstrual pain to understand why some don't get relief from NSAIDs like ibuprofen. Researchers measured pain sensitivity and brain processing to see if changes in the nervous system (central sensitization) play a role. The goal is to iden…

This study looked at 164 teenage girls aged 13-19 with painful periods to understand how their brains process pain. Researchers used brain scans and pain tests to see if certain brain patterns predict whether menstrual pain becomes long-term. The goal is to find early warning sig…

This study involved 83 adults recently diagnosed with borderline personality disorder (BPD). Participants watched educational videos about BPD or other topics and completed daily surveys about their emotions and social interactions. The goal was to see if learning more about BPD …

This study looked at how stress and negative emotions influence eating choices in women with binge-eating disorder. Researchers used brain scans to see how decision-making areas respond under stress. The goal was to better understand the link between emotions, brain activity, and…

This study tested whether therapists looking at patients' electronic messages (like texts and emails) during sessions could improve treatment for anxiety and depression. About 110 adults in ongoing therapy participated. The goal was to see if this approach boosts quality of life …

This study looked at healthy girls aged 12-14 and their mothers to find early signs of depression. Researchers used interviews, computer tasks, saliva samples, and brain scans to see how mood and brain activity are linked. The goal was to learn more about what might predict depre…

This study looked at how pain affects opioid cravings in 89 adults with opioid use disorder and chronic pain. Participants attended a brief education session and then had their pain response measured. Researchers wanted to see if there is a link between how people react to pain a…

This study aimed to find out if brain scans and simple behavior tests can help doctors choose the right antidepressant for people with depression who also have anhedonia (loss of interest or pleasure). 133 adults with major depression completed brain imaging and reward-based task…

This study tested a telehealth program called CRAFT-EP that helps families support a relative with early psychosis and substance use (like alcohol or cannabis). 65 family members took part. The goal was to see if the program improves family wellbeing, including depression and anx…