Brain training shows promise for bipolar thinking problems

NCT ID NCT01470781

First seen Jun 25, 2026 · Last updated Jun 27, 2026 · Updated 1 time

Summary

This study tested a computer program called BrainWorks that uses fun games to train thinking skills like memory, attention, and problem-solving. 72 adults with bipolar disorder and psychosis played these games over several sessions. Researchers measured changes in cognitive abilities and daily functioning compared to a control group. The goal was to see if this brain training could help with the thinking problems that often come with bipolar disorder.

What this could mean

Our plain-language read of the trial. This is informational only — not medical advice or a prediction.

Active substance

BrainWorks computer-based cognitive training program

What this could lead to

If it works, this could point toward a non-drug way to sharpen memory, attention, and problem-solving skills in people with bipolar disorder.

What could go wrong

This is a small, completed study with only 72 participants, so results may not apply to everyone. The training is time-consuming and may not improve real-world functioning.

Disclaimer Read more

This is a summary of the original study . Summaries may miss details or leave out important information. Before applying or accepting participation, make sure you have read and understood the full study. Curemydisease.com takes no responsibility whatsoever for anything missed, misunderstood, or acted upon as a result of our summary — we know it does not capture everything.

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Conditions

The condition(s) this trial relates to.

bipolar disorder psychotic disorder Psychotic Disorders

As listed by the trial registrant

The condition terms exactly as the trial's registrant entered them.

Contacts and locations

Locations

  • McLean Hospital

    Belmont, Massachusetts, 02478, United States