M.d. Anderson Cancer Center
Clinical trials sponsored by M.d. Anderson Cancer Center, explained in plain language.
-
New hope for Hard-to-Treat breast cancer: drug combo shrinks tumors before surgery
Disease control CompletedThis study tested a combination of three drugs (panitumumab, carboplatin, and paclitaxel) given before surgery to women with triple-negative breast cancer that did not respond to standard chemotherapy. The goal was to shrink tumors enough to allow less extensive surgery. The tria…
Phase: PHASE2 • Sponsor: M.D. Anderson Cancer Center • Aim: Disease control
Last updated Apr 26, 2026 20:03 UTC
-
Immune boosting combo shows promise for Hard-to-Treat lymphomas
Disease control CompletedThis study tested a new treatment for people with certain types of lymphoma (Hodgkin or non-Hodgkin) that returned or didn't respond to standard therapy. The treatment combines a special antibody (AFM13) with immune cells called natural killer (NK) cells from donated umbilical co…
Phase: PHASE1, PHASE2 • Sponsor: M.D. Anderson Cancer Center • Aim: Disease control
Last updated Apr 26, 2026 20:02 UTC
-
New combo therapy shows promise for tough lymphoma cases
Disease control CompletedThis study tested a combination of the immunotherapy drug pembrolizumab and targeted radiation in 17 patients with non-Hodgkin lymphoma that had returned or stopped responding to treatment. The goal was to see if adding radiation could help the immune system fight the cancer bett…
Phase: PHASE2 • Sponsor: M.D. Anderson Cancer Center • Aim: Disease control
Last updated Apr 26, 2026 20:01 UTC
-
New combo therapy targets tough pancreatic cancer in early trial
Disease control CompletedThis early-phase trial tested a combination of two drugs—binimetinib and hydroxychloroquine—in 34 people with advanced pancreatic cancer that has a specific gene change (KRAS mutation) and has spread to other parts of the body. The goal was to find the safest dose of hydroxychlor…
Phase: PHASE1 • Sponsor: M.D. Anderson Cancer Center • Aim: Disease control
Last updated Apr 26, 2026 20:01 UTC
-
New drug combo shows promise in slowing prostate cancer spread
Disease control CompletedThis study looked at whether adding the drug axitinib to standard hormone therapy before surgery could help control prostate cancer that had spread to lymph nodes. 73 men with previously untreated prostate cancer took part. The goal was to see if the combination delayed cancer pr…
Phase: PHASE2 • Sponsor: M.D. Anderson Cancer Center • Aim: Disease control
Last updated Apr 26, 2026 20:00 UTC
-
Could adding erlotinib to chemo shrink head and neck tumors better?
Disease control CompletedThis study looked at whether adding the targeted drug erlotinib to standard chemotherapy (docetaxel plus cisplatin or carboplatin) helps shrink head and neck tumors more than chemo alone before surgery. About 55 adults with advanced but operable head and neck cancer took part. Th…
Phase: PHASE2 • Sponsor: M.D. Anderson Cancer Center • Aim: Disease control
Last updated Apr 26, 2026 20:00 UTC
-
New drug shows promise for rare, hard-to-treat cancers
Disease control CompletedThis study tested a drug called sintilimab in 10 people with advanced cancer of unknown primary (CUP) that had not responded to standard chemotherapy. Sintilimab is an immunotherapy that helps the immune system attack cancer cells. The goal was to see if the drug could shrink tum…
Phase: PHASE2 • Sponsor: M.D. Anderson Cancer Center • Aim: Disease control
Last updated Apr 26, 2026 20:00 UTC
-
New staging method could sharpen lung cancer radiation decisions
Diagnosis CompletedThis study looked at whether adding a special scope test (EBUS-TBNA) after a standard PET/CT scan can more accurately stage early-stage non-small cell lung cancer. About 150 patients with stage I-IIA cancer who were being considered for radiation therapy took part. The goal was t…
Sponsor: M.D. Anderson Cancer Center • Aim: Diagnosis
Last updated Apr 26, 2026 20:02 UTC
-
New mammogram technique spots hidden breast cancers
Diagnosis CompletedThis study tested whether contrast-enhanced mammography (CEM) can find breast cancers that standard mammograms miss. 89 women already diagnosed or highly suspected of having breast cancer received CEM, which uses an iodine dye to make tumors stand out. The goal was to see if CEM …
Phase: NA • Sponsor: M.D. Anderson Cancer Center • Aim: Diagnosis
Last updated Apr 26, 2026 20:02 UTC