Could adding erlotinib to chemo shrink head and neck tumors better?

NCT ID NCT01927744

First seen Jan 09, 2026 · Last updated Jun 16, 2026 · Updated 23 times

Summary

This study tested whether adding the targeted drug erlotinib to standard chemotherapy (docetaxel plus cisplatin or carboplatin) could improve tumor shrinkage before surgery in people with advanced head and neck cancer. About 55 adults with surgically removable tumors took part. The main goal was to see if the combination led to fewer live cancer cells left in the removed tumor compared to chemo plus a placebo.

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Contacts and locations

Locations

  • University of Texas MD Anderson Cancer Center

    Houston, Texas, 77030, United States

Conditions

Explore the condition pages connected to this study.