New hope for Hard-to-Treat breast cancer: drug combo shrinks tumors before surgery

NCT ID NCT02593175

First seen Nov 06, 2025 · Last updated Apr 25, 2026 · Updated 25 times

Summary

This study tested a combination of three drugs (panitumumab, carboplatin, and paclitaxel) given before surgery to women with triple-negative breast cancer that did not respond to standard chemotherapy. The goal was to shrink tumors enough to allow less extensive surgery. The trial involved 43 participants with early-stage breast cancer that had not spread beyond the breast or nearby lymph nodes.

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Contacts and locations

Locations

  • M D Anderson Cancer Center

    Houston, Texas, 77030, United States

Conditions

Explore the condition pages connected to this study.