Jules Bordet Institute

This study is testing if a much shorter, more intense radiation schedule can control prostate cancer that returns after surgery as well as the standard, longer treatment. It will compare a 5-session treatment to the usual 20-35 sessions. The main goal is to see if the shorter tre…

This study compares two standard treatment approaches for older adults (age 70+) with locally advanced rectal cancer. Researchers want to determine whether giving all chemotherapy before surgery works better and is safer than the traditional approach of giving some chemotherapy a…

This study is for people with advanced HER2-positive breast cancer whose disease has worsened on a specific drug (T-DXd). It tests if a special imaging scan (HER2-PET/CT) can predict who might benefit from switching to another targeted drug (T-DM1). Patients get the scan and a bi…

This study is for women with a specific type of advanced breast cancer (ER+/HER2-) whose current hormone-based medications are starting to fail at 1-3 spots in the body. Researchers want to see if using very precise, high-dose radiation (called SBRT) on just those few growing tum…

This study tests whether regular testosterone injections can improve quality of life for men with low testosterone who are receiving end-of-life care. Researchers will give injections every two weeks to 20 men and track changes in their daily function, symptoms, and comfort. The …

This study aims to understand why some prostate cancer patients don't respond to a targeted radiation treatment called 177Lu-PSMA-RLT. Researchers will measure how much radiation reaches tumors after one treatment cycle to see if this measurement can predict which patients will u…

This research program aims to better understand how and why cancer spreads to the brain and spinal cord (CNS metastases) in patients with solid tumors like breast cancer, lung cancer, and melanoma. It will enroll 600 patients at high risk for this complication to collect detailed…

This study looks back at the medical records of 500 patients who had major surgery for advanced abdominal cancers. The goal is to understand how often a painful complication called an incisional hernia happens after this surgery, what factors make it more likely, and how surgeons…