New trial tests faster radiation for prostate cancer relapse

NCT ID NCT06523634

First seen Jun 25, 2026 · Last updated Jun 27, 2026 · Updated 1 time

Summary

This study compares a shorter, high-dose radiation treatment (SBRT) to standard radiation for men whose prostate cancer has come back after surgery. About 284 men will be randomly assigned to one of the two approaches. The goal is to see if SBRT is as safe and effective, with fewer side effects on bowel and urinary function.

What this could mean

Our plain-language read of the trial. This is informational only — not medical advice or a prediction.

Active substance
Stereotactic body radiotherapy (SBRT)
What this could lead to
If successful, this could offer a shorter, more convenient radiation option for men with prostate cancer recurrence after surgery, with similar or better quality of life.
What could go wrong
This is a phase II/III trial, so results are not yet confirmed. SBRT may cause different side effects, and it may not control the cancer as well as standard radiation in the long term.

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Conditions

The condition(s) this trial relates to.

As listed by the trial registrant

The condition terms exactly as the trial's registrant entered them.

Contacts and locations

Locations

  • AZ Groeninge

    RECRUITING

    Kortrijk, Belgium

  • AZ Sint Jan

    RECRUITING

    Bruges, Belgium

  • AZ Sint-Maarten

    RECRUITING

    Mechelen, Belgium

  • AZorg

    RECRUITING

    Aalst, Belgium

  • CHU HELORA - Hôpital de La Louvière - site Jolimont

    RECRUITING

    La Louvière, Belgium

    Contact Email: •••••@•••••

  • CHU UCL Namur - Site Elisabeth

    RECRUITING

    Namur, Belgium

  • Cliniques universitaires Saint-Luc (UCLouvain)

    RECRUITING

    Woluwe-Saint-Lambert, Belgium

    Contact Email: •••••@•••••

  • Jessa Ziekenhuis

    RECRUITING

    Hasselt, Belgium

    Contact Email: •••••@•••••

  • Jules Bordet Institute, H.U.B

    RECRUITING

    Brussels, Belgium

  • UZ Gent

    RECRUITING

    Ghent, Belgium

  • UZ Leuven

    RECRUITING

    Leuven, Belgium

  • Ziekenhuis Aan de Stroom (ZAS)

    RECRUITING

    Antwerp, Belgium

  • Ziekenhuis Oost-Limburg (ZOL) Campus Sint-Jan

    RECRUITING

    Genk, Belgium

    Contact Email: •••••@•••••

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