Personalized radiation dosing may improve prostate cancer therapy

NCT ID NCT07370597

First seen Jun 27, 2026 · Last updated Jun 27, 2026

Summary

This study looks at whether measuring the exact radiation dose delivered to tumors can predict which patients with advanced prostate cancer will respond to a targeted radioactive therapy called Lu-177 PSMA. Researchers will track 110 men over 12 weeks to see if dose calculations after the first treatment cycle can identify non-responders early. The goal is to personalize treatment by adjusting doses or cycles for each patient.

What this could mean

Our plain-language read of the trial. This is informational only — not medical advice or a prediction.

Active substance

Lutetium-177 PSMA radioligand therapy

What this could lead to

If successful, this could allow doctors to personalize radiation doses for prostate cancer patients, potentially improving response rates and reducing ineffective treatments.

What could go wrong

This is an early-stage observational study (110 participants) that does not test a new treatment but rather a prediction method. The approach may not reliably predict outcomes, and results may not apply to all patients.

Disclaimer Read more

This is a summary of the original study . Summaries may miss details or leave out important information. Before applying or accepting participation, make sure you have read and understood the full study. Curemydisease.com takes no responsibility whatsoever for anything missed, misunderstood, or acted upon as a result of our summary — we know it does not capture everything.

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Conditions

The condition(s) this trial relates to.

adenocarcinoma castration-resistant prostate carcinoma prostate cancer

As listed by the trial registrant

The condition terms exactly as the trial's registrant entered them.

Contacts and locations

Study contacts

  • Contact

    Phone: •••-•••-•••• Email: •••••@•••••

Locations

  • Institut Jules Bordet

    RECRUITING

    Brussels, 1070, Belgium

    Contact Phone: •••-•••-•••• Email: •••••@•••••