Jaeb Center For Health Research

This study is testing whether an oral medication called tonabersat can reduce swelling in the retina (diabetic macular edema) in people who still have good vision. About 128 adults with type 1 or 2 diabetes will take either the drug or a placebo pill for 6 months to see if it thi…

This study is testing whether two lower doses of a medicine called bevacizumab can safely and effectively treat the most severe form of retinopathy of prematurity (ROP), an eye disease in very small premature babies. Doctors are comparing a very low dose (0.063 mg) to the standar…

This study aims to understand how quickly vision declines in people with a specific genetic cause of Usher syndrome, a condition that causes both hearing and vision loss. Researchers will follow 44 participants with PCDH15 gene mutations for four years, measuring their vision and…

This study aims to understand how vision changes over time in adults with a specific genetic form of retinitis pigmentosa (caused by EYS gene mutations). Researchers will observe 103 participants for four years, measuring their vision and eye structure in detail. The goal is to g…

This study aims to understand how body composition, muscle strength, and nutrition relate to lung function and overall health in adults with cystic fibrosis. Researchers will measure 300 participants using scans, strength tests, and questionnaires to create detailed health profil…

This study aims to understand how vision declines over time in people with USH2A gene mutations, which cause Usher syndrome type 2a and a form of retinitis pigmentosa. Researchers are following 127 patients for up to 9 years, measuring their vision and retinal health with various…

This study aims to understand how a rare genetic eye disease called gyrate atrophy progresses over four years in people who are following standard dietary treatment. Researchers will track changes in vision, eye structure, and blood levels in 46 participants to gather essential i…