Huashan Hospital

This trial investigates whether edaravone dexborneol sublingual tablets can improve blood-brain barrier function in people with CADASIL, a genetic condition that causes small strokes and cognitive decline. About 60 adults aged 18 to 80 with confirmed CADASIL will be observed for …

This pilot trial tests whether sirolimus, an anti-inflammatory drug, can reduce artery wall swelling in people with vertebrobasilar dolichoectasia (VBD), a condition where arteries at the base of the brain become enlarged and twisted. Twelve participants will take sirolimus daily…

This pilot study tests whether amiloride, a drug used for high blood pressure, can reduce inflammation in the walls of enlarged arteries at the base of the brain in people with vertebrobasilar dolichoectasia (VBD). Six adults with VBD will take amiloride for up to 12 months. Rese…

This early-stage trial is testing a new treatment called C-CAR168, which uses a patient's own immune cells modified to attack harmful cells in the body. It is for 15 adults with multiple sclerosis, neuromyelitis optica, autoimmune encephalitis, or stiff person syndrome that have …

This trial is testing whether adding a targeted drug called orelabrutinib to standard chemotherapy can improve outcomes for people newly diagnosed with primary central nervous system lymphoma, a rare type of brain cancer. About 215 participants will be randomly assigned to one of…

This study is developing an artificial intelligence (AI) system that can analyze standard MRI brain scans to determine the specific molecular subtype of a child's brain tumor before surgery. The research includes 1,400 children under 18 with suspected brain tumors, using both pas…

This study follows thousands of people with chronic kidney disease (stages 3 to 5) to understand how the disease progresses and leads to complications. Researchers will collect data from medical records and existing patient groups to build models that could help doctors make bett…

This study develops an artificial intelligence model that can classify brain tumors into categories, families, and specific diagnoses using only standard stained tissue slides. Researchers will train the AI on 20,000 archived images from two hospitals and test its accuracy agains…

This research project aims to understand why older adults get more infections and why those infections can be more serious. By following 23,000 people aged 60 and older, scientists will collect health data and samples like blood and stool to study how the immune system changes wi…

This study will test whether an artificial intelligence (AI) tool can help doctors review complete blood count (CBC) results faster than the current manual process. About 20,000 people who already need a routine blood test will have their results analyzed by the AI, with no extra…

This study will use artificial intelligence to analyze data from over 31,000 tuberculosis patients. The goal is to create a system that helps doctors decide which patients can be cured with a short treatment course and which need longer therapy. The AI will be tested to see if it…

This study looks at whether the placement of hand sanitizer in a doctor's office affects how much psoriasis patients trust their doctor and feel stigmatized. Researchers will observe doctors' hand hygiene habits and ask 250 patients to fill out questionnaires. The goal is to find…

This study looks at whether a special PET scan (18F-AGX) can detect early changes in brain tumor activity in adults with slow-growing IDH-mutant gliomas who are taking the drug Vorasidenib. Ten participants will get the drug daily for about a year and have multiple PET and MRI sc…