Huashan Hospital

This study tests whether adding the targeted drug orelabrutinib to standard chemotherapy improves outcomes for people newly diagnosed with primary central nervous system lymphoma (a rare brain cancer). About 215 adults aged 18-75 will be randomly assigned to one of three treatmen…

This early-phase study tests a new treatment called C-CAR168, made from a patient's own immune cells, for people with severe central nervous system autoimmune diseases like multiple sclerosis and neuromyelitis optica that haven't responded to standard treatments. The therapy targ…

This study looks at how things like air pollution, noise, and lack of green spaces in cities may affect mental health. Researchers will track 680 people with depression, anxiety, or alcohol use disorder, plus healthy volunteers, using wearable devices and a smartphone app. The go…

This study looks at whether a special PET scan (18F-AGX) can detect early changes in brain tumors (low-grade IDH-mutant gliomas) during treatment with the drug Vorasidenib. Ten adults with recurrent or residual tumors will receive the drug and undergo both MRI and PET scans over …