Experimental CAR-T therapy targets tough brain diseases

NCT ID NCT07341828

First seen Jan 23, 2026 · Last updated May 10, 2026 · Updated 21 times

Summary

This early-phase study tests a new treatment called C-CAR168, made from a patient's own immune cells, for people with severe central nervous system autoimmune diseases like multiple sclerosis and neuromyelitis optica that haven't responded to standard treatments. The therapy targets two proteins (CD20 and BCMA) to help control the disease. The main goal is to check safety and find the right dose in 15 adults.

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