First Affiliated Hospital Of Wenzhou Medical University

This study is testing a new surgical technique for early-stage cancer in the upper part of the stomach. It compares removing just the cancerous portion of the stomach (which aims to preserve digestive function) against the standard procedure of removing the entire stomach. The ma…

This study compares two steroid treatment lengths for adults with a specific kidney condition called steroid-sensitive nephrotic syndrome. Researchers want to see if a 12-week steroid course works as well as the standard 24-week treatment at preventing the disease from returning.…

This study is testing if popular weight-loss drugs (semaglutide/Ozempic and tirzepatide/Mounjaro) can improve fertility in obese men. About 180 married men, aged 20-45 with obesity-related infertility, will receive either lifestyle advice alone or weekly injections of one of the …

This study aims to find the best surgical technique for women with mid-to-low rectal cancer. Researchers will compare two different ways of performing the main surgery to see which one reduces bleeding during the operation and helps patients recover better afterwards. The trial w…

This study is testing a drug called inectolizumab for people newly diagnosed with a rare autoimmune disease that attacks the nerves and spinal cord (NMOSD). The main goal is to see if the drug can help control the disease while allowing patients to take fewer steroids, which have…

This study is testing if adding a short, precise course of radiation (SBRT) to standard chemotherapy and immunotherapy before surgery works better for shrinking high-risk, hormone-positive breast cancer. About 302 patients will be randomly assigned to receive either the standard …

This study is testing two biologic drugs, risankizumab and ustekinumab, for people with a severe form of Crohn's disease where the intestines develop scar tissue and narrow. It's for patients whose current treatments have stopped working. The goal is to see if these drugs can pre…

This study is for adults with a high-risk type of bladder cancer that has not responded to or cannot tolerate the standard BCG treatment. It will compare a two-part treatment (an immunotherapy drug given through a vein plus two chemotherapy drugs placed directly into the bladder)…

This study aims to determine whether it's safer for patients with clogged heart arteries to have their artery-opening procedure before or after they undergo other planned, time-sensitive surgeries like cancer operations. Researchers will compare two approaches in 140 patients: do…

This is an early, first-in-human study to test the safety and find the right dose of a new treatment called CBG131 for adults with advanced stomach or pancreatic cancer. The treatment involves collecting a patient's own immune cells, engineering them in a lab to target a specific…

This study aims to see if adjusting the timing of immunotherapy based on daily blood tests improves treatment for adults with advanced non-small cell lung cancer. Researchers will compare giving immunotherapy on the same day as chemotherapy, on a fixed later day, or on a personal…

This study is testing a new high-tech system for knee surgery in people with osteoarthritis. The system combines 3D planning, custom 3D-printed guides, and augmented reality during surgery to try to improve knee alignment and reduce stress on the joint. Researchers will compare t…

This study is testing if ondansetron, a medicine often used for nausea, can help reduce the harmful side effects caused by powerful immunotherapy drugs used to treat liver cancer. It will involve 66 patients who are scheduled to receive standard immunotherapy. Researchers will co…

This study tests three different digital foot care approaches to see which works best at preventing foot ulcers in people with diabetes. It will involve over 1,500 high-risk participants who will use smartphone apps to monitor their feet. The goal is to find the most effective an…

This study aims to create an artificial intelligence (AI) tool that can predict how well patients with advanced liver cancer will respond to a specific combination of two drugs. Researchers will look back at the medical records and CT scans of 400 patients who have already receiv…