Could ozempic help men become fathers? new trial investigates
NCT ID NCT07179120
First seen Jun 25, 2026 · Last updated Jun 26, 2026 · Updated 1 time
Summary
This study tests whether two popular weight-loss drugs, semaglutide and tirzepatide, can improve sperm quality and help obese men have children naturally. About 180 men will receive either lifestyle advice, semaglutide, or tirzepatide for 32 weeks. Researchers will measure changes in sperm count, movement, and pregnancy rates in their partners.
What this could mean
Our plain-language read of the trial. This is informational only — not medical advice or a prediction.
- Active substance
- Semaglutide (Rybelsus) and Tirzepatide (Mounjaro) – weekly injections
- What this could lead to
- If successful, these drugs could offer a new way to improve sperm quality and natural pregnancy rates in obese men struggling with infertility.
- What could go wrong
- This is an early phase 2 trial with only 180 men, so results may not apply to everyone. Side effects like nausea and rare risks (pancreatitis) are possible.
This is an AI summary of the original study and may miss details. Read our disclaimer.
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Conditions
The condition(s) this trial relates to.
As listed by the trial registrant
The condition terms exactly as the trial's registrant entered them.