Radiation plus Chemo-Immunotherapy shows promise in High-Risk breast cancer trial

NCT ID NCT07254858

First seen Jun 27, 2026 · Last updated Jun 27, 2026

Summary

This study tests whether adding targeted radiation (SBRT) to standard chemotherapy and immunotherapy before surgery can improve outcomes for people with a common, high-risk breast cancer type (HR+/HER2-). About 302 participants will be randomly assigned to receive either chemo-immunotherapy alone or with the added radiation. The goal is to see if the combination leads to a higher rate of tumor disappearance by the time of surgery and better long-term survival.

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This is a summary of the original study . Summaries may miss details or leave out important information. Before applying or accepting participation, make sure you have read and understood the full study. Curemydisease.com takes no responsibility whatsoever for anything missed, misunderstood, or acted upon as a result of our summary — we know it does not capture everything.

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Conditions

The condition(s) this trial relates to.

breast neoplasm hormone receptor-positive breast cancer

As listed by the trial registrant

The condition terms exactly as the trial's registrant entered them.

Contacts and locations

Locations

  • The First Affiliated Hospital of Wenzhou Medical University

    Wenzhou, Zhejiang, China

    Contact Phone: •••-•••-•••• Email: •••••@•••••