Stomach-Saving surgery could help cancer patients keep weight on

NCT ID NCT07260461

Not yet recruiting Disease control Sponsor: First Affiliated Hospital of Wenzhou Medical University Source: ClinicalTrials.gov ↗

First seen Jun 24, 2026 · Last updated Jun 27, 2026 · Updated 1 time

Summary

This study compares a new, less invasive surgery that removes only the cancerous upper part of the stomach to the standard full stomach removal. The goal is to see if the new approach helps patients lose less weight one year after surgery. The trial will enroll 120 adults with early-stage stomach cancer and track their weight, quality of life, and side effects.

What this could mean

Our plain-language read of the trial. This is informational only — not medical advice or a prediction.

Active substance: Laparoscopic proximal gastrectomy with tubular stomach-based right-opening single flap valvuloplasty (LPG-tbROSF)
What this could lead to: If successful, this new surgery could help patients with early stomach cancer keep more of their stomach, leading to better nutrition and less weight loss after recovery.
What could go wrong: This is a small, early-stage trial with only 120 patients, so results may not apply to everyone. The new surgery may not control cancer as well as total removal, and there is a risk of acid reflux or other complications.

This is an AI summary of the original study and may miss details. Read our disclaimer.

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Conditions

The condition(s) this trial relates to.

gastric cardia adenocarcinoma gastric neoplasm gastroesophageal cancer gastroesophageal junction adenocarcinoma

As listed by the trial registrant

The condition terms exactly as the trial's registrant entered them.

ADENOCARCINOMA - GASTROESOPHAGEAL JUNCTION (GEJ) GASTROESOPHAGEAL JUNCTION CANCER STOMACH NEOPLASMS

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