First Affiliated Hospital Of Chongqing Medical University

This very early study will test the drug talquetamab in just 2 people with refractory generalized myasthenia gravis, a chronic autoimmune disease that causes muscle weakness. The drug is designed to help the immune system attack the cells that produce harmful antibodies. The goal…

This study tests a combination of three drugs—ivarmacitinib, camrelizumab, and apatinib—in 65 people with advanced liver cancer that has stopped responding to initial immunotherapy. The goal is to see if this triple therapy can shrink tumors or slow disease progression. Participa…

This pilot study tests whether a non-invasive brain stimulation technique called tACS can help teens (ages 12-18) with major depression when added to their usual medication. Thirty participants will receive either real or sham stimulation daily for several weeks. The goal is to s…

This study tests whether monoclonal antibodies can safely and effectively treat acute attacks of neuromyelitis optica spectrum disorder (NMOSD), a rare disease that causes inflammation in the eyes and spinal cord. Researchers will enroll 40 adults experiencing a recent flare-up a…

This pilot study will test a type of brain stimulation called accelerated intermittent theta-burst stimulation (a-iTBS) in 45 adolescents aged 12-18 with major depressive disorder. Participants will get either real or sham stimulation, guided by MRI scans. The goal is to see if i…

This Phase 2 trial will test whether adding selenium supplements to standard antidepressant medication (fluoxetine) can improve depression symptoms in 172 children and adolescents aged 12-18 with major depressive disorder. Participants will receive either selenium or a placebo fo…

This pilot study tests whether a non-invasive device that sends a mild alternating current to the brain (tACS) can safely ease depression symptoms in 30 teenagers who have never taken antidepressants. Participants will receive daily sessions over several weeks, and researchers wi…

This observational study will compare the gut and urine bacteria, as well as metabolic profiles, of 120 people with ureteral stricture (a narrowing of the tube from kidney to bladder) against healthy volunteers. Researchers aim to find differences that could explain why the condi…