Could a common mineral ease teen depression? new trial investigates
NCT ID NCT07203144
First seen Jun 27, 2026 · Last updated Jun 27, 2026
Summary
This Phase 2 trial will test whether adding selenium supplements to standard antidepressant medication (fluoxetine) can improve depression symptoms in 172 children and adolescents aged 12-18 with major depressive disorder. Participants will receive either selenium or a placebo for 8 weeks, and researchers will track changes in depression scores, brain scans, and biological samples. The goal is to see if selenium can safely boost treatment outcomes in young people.
What this could mean
Our plain-language read of the trial. This is informational only — not medical advice or a prediction.
Active substance
selenium yeast supplementation
What this could lead to
If it works, this could point toward a simple, safe supplement to boost the effectiveness of standard depression treatment in young people.
What could go wrong
This is a small, early-stage trial with only 172 participants. Selenium may not provide any additional benefit over standard treatment, and results may not apply to all young people with depression.
Disclaimer
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the original study
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Summaries may miss details or leave out important information. Before applying or accepting participation, make sure you have read and understood the full study. Curemydisease.com takes no responsibility whatsoever for anything missed, misunderstood, or acted upon as a result of our summary — we know it does not capture everything.
This is a summary of the original study . Summaries may miss details or leave out important information. Before applying or accepting participation, make sure you have read and understood the full study. Curemydisease.com takes no responsibility whatsoever for anything missed, misunderstood, or acted upon as a result of our summary — we know it does not capture everything.
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Conditions
The condition(s) this trial relates to.
As listed by the trial registrant
The condition terms exactly as the trial's registrant entered them.
Contacts and locations
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Study contacts
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Contact
Phone: •••-•••-•••• Email: •••••@•••••
Locations
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The First Affiliated Hospital of Chongqing Medical University
Chongqing, Chongqing Municipality, 40000, China
Contact Phone: •••-•••-•••• Email: •••••@•••••