Could a gentle brain current lift teen depression without drugs?

NCT ID NCT07185464

First seen Jun 26, 2026 · Last updated Jun 26, 2026

Summary

This pilot study tests whether a non-invasive device that sends a mild alternating current to the brain (tACS) can safely ease depression symptoms in 30 teenagers who have never taken antidepressants. Participants will receive daily sessions over several weeks, and researchers will track mood and anxiety changes. The goal is to see if this drug-free approach can help speed up recovery.

What this could mean

Our plain-language read of the trial. This is informational only — not medical advice or a prediction.

Active substance

transcranial alternating current stimulation (tACS) device

What this could lead to

If it works, this could point toward a drug-free treatment option for teenagers with first-episode depression.

What could go wrong

This is a very small pilot study (30 people) with no phase, so results are preliminary. It may not show clear benefit or could have unknown side effects.

Disclaimer Read more

This is a summary of the original study . Summaries may miss details or leave out important information. Before applying or accepting participation, make sure you have read and understood the full study. Curemydisease.com takes no responsibility whatsoever for anything missed, misunderstood, or acted upon as a result of our summary — we know it does not capture everything.

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Conditions

The condition(s) this trial relates to.

major depressive disorder

As listed by the trial registrant

The condition terms exactly as the trial's registrant entered them.

Contacts and locations

Study contacts

  • Contact

    Phone: •••-•••-•••• Email: •••••@•••••

Locations

  • The First Affiliated Hospital of Chongqing Medical University

    Chongqing, Chongqing Municipality, 40000, China

    Contact Phone: •••-•••-•••• Email: •••••@•••••