New triple therapy aims to outsmart drug-resistant liver cancer

NCT ID NCT07324473

First seen Jan 11, 2026 · Last updated May 24, 2026 · Updated 23 times

Summary

This study tests a three-drug combination (ivarmacitinib, camrelizumab, and apatinib) in 65 adults with advanced liver cancer that initially responded to immunotherapy but then stopped working. The goal is to see if adding a JAK inhibitor can re-sensitize the tumor to immune attack. Participants will receive treatment until the cancer progresses or side effects become unacceptable, for up to 2 years.

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Contacts and locations

Locations

  • The First Affiliated Hospital of Chongqing Medical University

    Chongqing, Chongqing Municipality, China

    Contact Phone: •••-•••-•••• Email: •••••@•••••

Conditions

Explore the condition pages connected to this study.