New cocktail aims to outsmart Drug-Resistant liver cancer

NCT ID NCT07324473

First seen Jun 27, 2026 · Last updated Jun 27, 2026

Summary

This study tests a combination of three drugs—ivarmacitinib, camrelizumab, and apatinib—in 65 people with advanced liver cancer that has stopped responding to initial immunotherapy. The goal is to see if this triple therapy can shrink tumors or slow disease progression. Participants will receive the drugs for up to 2 years, with regular imaging scans to track results.

What this could mean

Our plain-language read of the trial. This is informational only — not medical advice or a prediction.

Active substance
Ivarmacitinib, Camrelizumab, and Apatinib
What this could lead to
If it works, this could offer a new treatment option for people with advanced liver cancer whose tumors have stopped responding to standard immunotherapy.
What could go wrong
This is an early Phase 2 study with only 65 people, so results may not apply to everyone. The triple-drug combination also carries risks of serious side effects.

This is an AI summary of the original study and may miss details. Read our disclaimer.

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Conditions

The condition(s) this trial relates to.

As listed by the trial registrant

The condition terms exactly as the trial's registrant entered them.

Contacts and locations

Locations

  • The First Affiliated Hospital of Chongqing Medical University

    Chongqing, Chongqing Municipality, China

    Contact Phone: •••-•••-•••• Email: •••••@•••••

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