Scientists hunt for clues in gut and urine to understand urinary blockages

NCT ID NCT07409870

First seen Jun 24, 2026 · Last updated Jun 27, 2026 · Updated 1 time

Summary

This observational study will compare the gut and urine bacteria, as well as metabolic profiles, of 120 people with ureteral stricture (a narrowing of the tube from kidney to bladder) against healthy volunteers. Researchers aim to find differences that could explain why the condition develops and identify potential markers for diagnosis. Participants provide stool, urine, and blood samples and undergo standard imaging and lab tests.

What this could mean

Our plain-language read of the trial. This is informational only — not medical advice or a prediction.

What this could lead to
If successful, this could identify new biomarkers for diagnosing or monitoring ureteral stricture, and point toward future microbiome-based treatments.
What could go wrong
This is an early observational study, not a treatment trial. It may not find clear differences, and any discoveries would need years of further research to become useful.

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Conditions

The condition(s) this trial relates to.

As listed by the trial registrant

The condition terms exactly as the trial's registrant entered them.

Contacts and locations

Locations

  • Department of Urology, The First Affiliated Hospital of Chongqing Medical University

    Chongqing, 400016, China

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Other studies related to the condition(s) this trial covers.