Dartmouth-hitchcock Medical Center

This study tested a doctor-designed dose adjustment algorithm to prevent unplanned delays in FOLFOX chemotherapy for people with cancers of the colon, stomach, esophagus, and other digestive organs. 52 adults participated, and the goal was to see if the algorithm could keep treat…

This completed study tested a high-density EEG (using up to 256 electrodes) to map brain areas involved in movement, sensation, language, and emotion. It included 122 people with epilepsy, brain tumors, or healthy controls. The goal was to see if this technique can more precisely…

This study tested whether a special camera that uses near-infrared light and a dye can help doctors diagnose acute compartment syndrome—a dangerous condition where pressure builds up in muscles after a severe injury. Researchers observed 15 adults with suspected compartment syndr…

This study compared three common blood thinners—aspirin, warfarin, and rivaroxaban—to prevent dangerous blood clots after hip or knee replacement surgery. Nearly 19,000 adults took part. The goal was to find which option best balances preventing clots with avoiding bleeding side …

This study tested a 6-session virtual group program for new mothers with pelvic floor issues like pain or incontinence after childbirth. The group taught coping skills and education to improve quality of life. Sixteen participants joined to see if the program was helpful and easy…

This study compared two numbing creams for pain during skin treatments like laser and microneedling. 63 adults rated their pain after using either a standard 4% lidocaine cream or a stronger mix of three anesthetics. The goal was to see which cream provides better pain relief dur…

This study tested a short, four-session therapy program for people who worry excessively about their health. Medical assistants delivered the therapy in primary care clinics. 68 adults took part, and the study measured changes in health anxiety over 12 weeks. The goal was to see …

This study tested whether a sous vide device, normally used for cooking, can keep a warm water bath at a steady temperature to rewarm frostbitten hands and feet. Seven people with acute frostbite took part. Researchers measured how long it took for the frozen areas to become warm…

This study tested whether wearing essential oil patches could lower stress and burnout in nurses working on a medical-surgery unit. Twenty nurses took part over 30 days, using the patches during their shifts and completing surveys about their stress levels. The goal was to see if…

This study tested a type of talk therapy called Positive Psychotherapy (PPT) to help people with serious mental illness quit smoking. Sixteen adults who smoked at least 10 cigarettes a day and wanted to quit took part. The goal was to see if at least 20% could stop smoking comple…

This study tested whether using forceps to help guide a tube into the bile duct during an ERCP procedure makes the process easier and reduces the chance of pancreatitis afterward. 152 patients were randomly assigned to either standard cannulation or forceps-assisted cannulation. …

This study explores whether an online educational video can help people living in rural parts of New Hampshire and Vermont learn about cancer research and clinical trials. Researchers will measure changes in knowledge, attitudes, and actual enrollment in cancer studies over six m…

This study tested a new way to measure blood flow in broken bones using a safe dye and a special camera. Researchers followed 104 fracture patients to see if poor blood flow leads to infections or other complications. The goal was to learn how to better predict and treat bone inf…

This study tested an educational program to help people in rural areas learn more about colorectal cancer screening. 205 adults aged 45-74 from specific counties in New Hampshire and Vermont took part. Researchers measured changes in knowledge and intentions to get screened befor…

This study looked at whether monitoring brain waves during general anesthesia can help predict if older adults (over 60) will experience memory or thinking problems after surgery. Researchers tracked 31 patients having elective, non-cardiac surgery and compared their brain activi…

This study looked at whether cannabis or a similar drug (dronabinol) can improve brain reward function in people with schizophrenia who also use cannabis. 263 participants took part to see if these substances help regulate brain circuits linked to motivation and pleasure. The goa…

This study tested a new handheld device that measures a natural chemical called protoporphyrin IX in the skin. This chemical is important for photodynamic therapy, a light-based treatment for certain skin conditions. Researchers measured the chemical levels in 219 adults at diffe…

This completed study looked at how physical fitness influences the way children (ages 8-17) process a high-fat meal. Fifteen kids drank a high-fat shake, and researchers measured how well their bodies broke down fats. The goal was to see if fitter children handle fatty meals bett…

This study looked at how a tiny, painless electric current to a part of the brain called the amygdala affects how people process emotions. Sixteen adults with epilepsy who already had brain electrodes in place viewed positive, negative, and neutral images while receiving random s…