Dartmouth-hitchcock Medical Center

This study tested a stem cell transplant using blood stem cells from a half-matched (haploidentical) donor for people with blood cancers like leukemia and lymphoma. The goal was to see how many patients survived and had successful engraftment by 100 days and one year after transp…

This study looked at patient satisfaction with two methods of managing difficulty urinating after gynecologic surgery: removing the catheter at home versus returning to the clinic. It focused on patients in rural areas who may have trouble traveling. The study was withdrawn befor…

This small pilot study tests whether a home-based program called HOBSCOTCH, originally designed for epilepsy, can be adapted for people with Parkinson's disease who have memory or thinking problems. Ten participants will work one-on-one with a coach in nine virtual sessions, lear…

This study tests a program called I-CARE for teens aged 12-17 who are in a medical hospital waiting for mental health treatment. The program uses videos and workbook activities to help lower emotional distress and suicidal thoughts. Researchers want to see if patients and staff f…

This study tests a 6-session virtual group program for new mothers with pelvic floor problems after childbirth. The group teaches coping skills, mindfulness, and education to improve quality of life. Sixteen participants will try the program to see if it's helpful and practical.

This study tests a simple goal-setting tool for people with knee pain or injury who are seeing an orthopedic surgeon. The tool helps patients identify specific, measurable, and time-bound goals for their treatment. The goal is to improve shared decision-making and make sure patie…

This study tests a new collapsible pessary (Reia pessary) for women with pelvic organ prolapse. The goal is to see if it allows patients to care for their prolapse on their own, instead of visiting a provider 2-4 times per year. About 120 current pessary users will try the device…

This small pilot study is testing whether a program called HOBSCOTCH, originally designed for epilepsy, can be adapted to help people with long COVID who have memory and thinking problems. Ten participants will attend nine virtual coaching sessions and complete surveys about thei…

This study tests whether a lower dose of Botox injected into the bladder can effectively reduce urgent, frequent urine leaks in women aged 70 and older, while possibly causing fewer side effects than the standard dose. About 376 women with overactive bladder that hasn't improved …

This small pilot study is testing whether a home-based program called HOBSCOTCH, originally designed for epilepsy, can be adapted to help people with multiple sclerosis (MS) who have memory and thinking difficulties. Eleven participants will work one-on-one with a coach in nine v…

This study tests a home-based program called HOBSCOTCH-PTE for people with epilepsy caused by a brain injury. The program aims to improve quality of life, memory, and thinking skills. It also helps caregivers by reducing their stress. The study includes 160 adults with post-traum…

This pilot study is testing a new exercise-focused group for adults who are overweight or have obesity. The goal is to see if the group helps people increase their physical activity without also increasing unhealthy eating or exercise behaviors. Twelve participants will wear Fitb…

This study looks at how the drug letrozole works in postmenopausal women with early-stage, hormone-sensitive breast cancer before they have surgery. About 178 participants will take letrozole for 4 to 24 weeks, and researchers will compare tumor samples taken before and after tre…

This study looks at whether measuring pressure waves in the epidural space can confirm correct placement as well as X-ray guidance does. About 160 adults having planned surgery with a thoracic epidural will have both methods tested. The goal is to see if the pressure method is a …

This study tests a new web-based tool designed to help transgender men and non-binary individuals make informed decisions about metoidioplasty or phalloplasty surgery. About 140 participants will be randomly assigned to use the tool or receive standard care, then complete surveys…