Dartmouth-hitchcock Medical Center
Clinical trials sponsored by Dartmouth-hitchcock Medical Center, explained in plain language.
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Can a tailored self-management program improve health outcomes for those with serious mental illness?
Disease control OngoingThis trial compares two group-based education programs for people with serious mental illness who also have chronic physical conditions like diabetes or heart disease. One program, Integrated Illness Management and Recovery (I-IMR), covers both mental and physical health self-man…
Phase: NA • Sponsor: Dartmouth-Hitchcock Medical Center • Aim: Disease control
Last updated Jul 24, 2026 00:00 UTC
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New study explores letrozole's effects on breast cancer before surgery
Disease control OngoingThis study tests the drug letrozole in postmenopausal women with early-stage ER+ breast cancer. Participants take letrozole for 4 to 24 weeks before surgery to see how the tumor changes and to check if they take the medication as prescribed. The goal is to improve treatment for t…
Phase: PHASE2 • Sponsor: Dartmouth-Hitchcock Medical Center • Aim: Disease control
Last updated Jun 27, 2026 12:39 UTC
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Can a Brain-Stiffness scan spot a treatable form of dementia?
Diagnosis OngoingThis trial tests whether magnetic resonance elastography (MRE), a special MRI that measures tissue stiffness, can distinguish normal pressure hydrocephalus from brain atrophy. Current scans often cannot tell the two apart, leading to missed or delayed diagnosis. Researchers will …
Phase: NA • Sponsor: Dartmouth-Hitchcock Medical Center • Aim: Diagnosis
Last updated Jul 24, 2026 00:00 UTC
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A digital bridge: could an online pathway ease depression in cancer care?
Symptom relief OngoingThis study tests an online pathway called iPath*D that guides cancer patients who report depression symptoms from screening to treatment options. The goal is to see if the tool is acceptable and easy to use for adults starting cancer treatment. Researchers will measure usability,…
Phase: NA • Sponsor: Dartmouth-Hitchcock Medical Center • Aim: Symptom relief
Last updated Aug 09, 2026 00:00 UTC
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Press play on better health: could recording doctor visits boost Self-Care in seniors?
Symptom relief OngoingThis trial tests whether giving older adults with diabetes and other chronic conditions audio recordings of their clinic visits helps them take a more active role in their own care. Participants either receive these recordings for a year or standard after-visit summaries. The stu…
Phase: NA • Sponsor: Dartmouth-Hitchcock Medical Center • Aim: Symptom relief
Last updated Aug 09, 2026 00:00 UTC
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Can a special exercise group boost activity without harm? small study aims to find out
Symptom relief ENROLLING_BY_INVITATIONThis pilot study tests a new group program called Move Healthier, designed to help people with overweight or obesity increase their exercise using cognitive and behavioral skills. The goal is to see if it boosts physical activity without raising the risk of disordered eating. Onl…
Phase: NA • Sponsor: Dartmouth-Hitchcock Medical Center • Aim: Symptom relief
Last updated Jul 30, 2026 00:00 UTC
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New video program aims to ease suicidal thoughts in hospitalized teens
Symptom relief OngoingThis study tests a program called I-CARE for teens aged 12-17 who are in a medical hospital waiting for mental health treatment after a suicide-related emergency. The program uses 7 short videos and workbook activities to help lower emotional distress and suicidal thoughts. Resea…
Phase: NA • Sponsor: Dartmouth-Hitchcock Medical Center • Aim: Symptom relief
Last updated Jun 27, 2026 13:02 UTC
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Can better sleep ease Crohn's symptoms? new study investigates
Symptom relief OngoingThis study looks at whether treating insomnia can help people with Crohn's disease feel better, including reducing pain and inflammation. About 83 adults with mild to moderate Crohn's and insomnia will receive a remote sleep treatment. The main goal is to see if the approach is p…
Phase: NA • Sponsor: Dartmouth-Hitchcock Medical Center • Aim: Symptom relief
Last updated Jun 27, 2026 12:36 UTC
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Rural patients may skip clinic visit by removing catheters at home
Symptom relief TerminatedThis study looked at how satisfied patients are with two ways of managing difficulty urinating after gynecologic surgery: having the catheter removed at the clinic or removing it themselves at home. The focus was on people living in rural areas who may have trouble traveling to a…
Phase: NA • Sponsor: Dartmouth-Hitchcock Medical Center • Aim: Symptom relief
Last updated Jun 27, 2026 12:02 UTC
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Knee patients try personalized goal program to boost treatment success
Symptom relief OngoingThis study tests a goal-setting program for adults with knee problems like arthritis or injuries. Participants work with their surgeon to create specific, measurable goals and track progress. The aim is to see if this approach helps patients achieve their treatment goals and impr…
Phase: NA • Sponsor: Dartmouth-Hitchcock Medical Center • Aim: Symptom relief
Last updated Jun 27, 2026 12:01 UTC
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Brain injury epilepsy study tests At-Home program to boost memory and ease caregiver burden
Symptom relief OngoingThis study tests a home-based program called HOBSCOTCH-PTE for people with epilepsy caused by a traumatic brain injury. The program aims to improve quality of life, memory, and thinking skills, and also helps support their caregivers. The study includes 160 adults with post-traum…
Phase: NA • Sponsor: Dartmouth-Hitchcock Medical Center • Aim: Symptom relief
Last updated Jun 27, 2026 11:03 UTC
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Can a phone app beat COVID brain fog? small study hopes to find out
Symptom relief OngoingThis pilot study tests whether a telehealth program called HOBSCOTCH-PACS can help people with long COVID manage memory and thinking problems. Ten participants will attend nine virtual coaching sessions and complete questionnaires about their quality of life and cognitive functio…
Phase: NA • Sponsor: Dartmouth-Hitchcock Medical Center • Aim: Symptom relief
Last updated Jun 27, 2026 09:06 UTC
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Less botox, same relief? new study tests lower dose for bladder leaks in women over 70
Symptom relief OngoingThis study looks at whether a lower dose of Botox injected into the bladder can effectively treat urgent, frequent bladder leaks in women aged 70 and older. The goal is to reduce symptoms and improve quality of life while possibly causing fewer side effects than the standard dose…
Phase: PHASE1, PHASE2 • Sponsor: Dartmouth-Hitchcock Medical Center • Aim: Symptom relief
Last updated Jun 27, 2026 09:01 UTC
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Can a home Brain-Training program ease Parkinson's memory woes?
Symptom relief OngoingThis pilot study tests whether a home-based program called HOBSCOTCH, originally designed for epilepsy, can be adapted for people with Parkinson's disease. Ten participants will work one-on-one with a coach in nine virtual sessions to learn problem-solving strategies and memory a…
Phase: NA • Sponsor: Dartmouth-Hitchcock Medical Center • Aim: Symptom relief
Last updated Jun 27, 2026 08:05 UTC
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New collapsible pessary could free women from frequent doctor visits
Symptom relief ENROLLING_BY_INVITATIONThis study tests a new collapsible pessary (Reia) for women with pelvic organ prolapse. The goal is to see if it allows patients to care for their prolapse on their own, instead of needing to visit a doctor 2-4 times per year. About 120 current pessary users will try the device a…
Phase: NA • Sponsor: Dartmouth-Hitchcock Medical Center • Aim: Symptom relief
Last updated Jun 27, 2026 07:59 UTC
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Can a home training program boost brain power in MS?
Symptom relief OngoingThis pilot study tests a home-based program called HOBSCOTCH, designed to help people with multiple sclerosis manage memory and thinking problems. Eleven participants will attend virtual coaching sessions and complete questionnaires about their quality of life and cognitive funct…
Phase: NA • Sponsor: Dartmouth-Hitchcock Medical Center • Aim: Symptom relief
Last updated Jun 27, 2026 07:59 UTC
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Scientists to peek inside nose to solve smell loss mystery
Knowledge-focused OngoingThis study will test a special microscope to look at the smell-sensing part of the nose in 36 adults undergoing sinus surgery. The goal is to see if the microscope can show differences between people with and without smell loss. This is an early-stage observation study, not a tre…
Phase: PHASE4 • Sponsor: Dartmouth-Hitchcock Medical Center • Aim: Knowledge-focused
Last updated Aug 16, 2026 00:00 UTC
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New online tool aims to ease tough surgery decisions for transgender individuals
Knowledge-focused ENROLLING_BY_INVITATIONThis study tests a new web-based tool designed to help people considering metoidioplasty or phalloplasty (gender-affirming surgeries) make more informed decisions. About 140 participants will either use the tool or receive standard care, then share feedback on how clear and helpf…
Phase: NA • Sponsor: Dartmouth-Hitchcock Medical Center • Aim: Knowledge-focused
Last updated Jun 27, 2026 12:00 UTC
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Could a simple pressure test replace x-rays for epidurals?
Knowledge-focused ENROLLING_BY_INVITATIONThis study compares two methods to confirm that an epidural needle is in the right spot: a pressure-based waveform analysis and traditional X-ray guidance. About 160 adults having planned surgery will receive both checks. The goal is to see if the pressure test is as accurate as …
Phase: NA • Sponsor: Dartmouth-Hitchcock Medical Center • Aim: Knowledge-focused
Last updated Jun 27, 2026 07:54 UTC