Dartmouth-hitchcock Medical Center

This early-phase trial tests a fluorescent dye called ABY-029 that makes cancer cells glow during surgery. The goal is to find the right dose so surgeons can better see and remove head and neck tumors. About 24 adults with operable head and neck cancer will receive a tiny amount …

This study tests whether a special sleep therapy (CBT-I) delivered over video calls can help adults with ulcerative colitis who also have insomnia. About 20 people will take part in 5 therapy sessions and complete online sleep diaries and questionnaires. The goal is to see if the…

This study aims to find out if using virtual reality headsets raises the risk of seizures in teenagers and adults with epilepsy. Researchers will monitor brain activity with EEG while participants wear a VR headset, first with the display off, then on without hand controllers, an…

This study looks at how lidocaine, a common numbing medicine, affects the electrical signals used to monitor nerves during spine surgery. 44 adults having spine surgery will get either lidocaine or a placebo through an IV. The goal is to see if lidocaine changes the threshold nee…

This small pilot study will test a structured list of discussion topics (called CKD Topics) designed to help patients with advanced chronic kidney disease, especially those living in rural areas, set the agenda for their clinic visits. The study involves 30 participants and focus…

This small pilot study will test whether a smartwatch can measure pain in people with knee osteoarthritis by tracking tiny electrical changes in their skin. Fifteen participants will wear the watch while doing simple tasks like walking and standing up from a chair. The goal is to…

This study looks at whether a non-invasive brain stimulation technique called transcranial magnetic stimulation can help people with OCD shift their behavior more flexibly. It will involve 12 adults with OCD and healthy volunteers. The goal is to see if the study procedures are p…

This study tests whether giving people a simple planning guide helps them complete their home stool test (FIT) for colorectal cancer screening. About 1600 adults aged 45-75 will be randomly assigned to receive the guide or not. Researchers will compare how many people finish the …

This study aims to better understand smell loss by using a special microscope to look directly at the smell-sensing tissue inside the nose. Researchers will compare images from people with and without smell problems to find differences. The goal is to develop a way to see and mea…

This study tests whether data from your smartphone (like activity and usage patterns) can warn doctors when depression symptoms are about to return. Researchers will track 320 adults who have been treated for depression and are currently well. If successful, this could lead to an…

This study looks at whether a tablet-based program called Plan & Protect can help teens who come to rural emergency rooms with suicidal thoughts or self-harm. The program guides teens and their parents on how to make the home safer by locking up medications and firearms. Research…

This study tests whether a special light treatment can help prevent infections in people with osseointegrated prostheses (implants that connect a prosthetic limb directly to bone). Ten adults with these implants will apply a cream to the skin around the implant and then use a lig…