Dartmouth-hitchcock Medical Center

This study tests whether giving a second, focused course of radiation to the breast is safe and effective for women whose breast cancer has returned more than a year after initial treatment. About 30 participants will receive accelerated partial breast irradiation. The goal is to…

This pilot study will test whether flushing the chest tube with saline alone can treat complicated pleural infections (fluid buildup around the lungs). If saline doesn't work, patients will receive stronger clot-busting drugs (fibrinolytics) or surgery. The study will track how l…

This early-phase trial tests a fluorescent dye called ABY-029 that may help surgeons see head and neck cancer during surgery. About 24 adults with head and neck squamous cell carcinoma will receive a tiny amount of the dye before surgery. Researchers will check safety and find th…

This study looks at better ways to screen caregivers of people with dementia for depression and connect them to online treatment. About 15 adult caregivers who show mild depression symptoms will test a new app. The goal is to see if the approach is easy to use and helps more peop…

This study looks at whether a type of brain stimulation called transcranial magnetic stimulation can help people with OCD shift their behavior more flexibly. It involves 12 participants who will receive three daily sessions of stimulation. The goal is to see if the procedures are…

This study will test whether using virtual reality headsets raises the risk of seizures in adolescents and adults with epilepsy. Forty participants will wear a VR headset while their brain activity is recorded with EEG, comparing periods with the display off, on, and with hand co…

This study will test a special microscope to look at the smell-sensing part of the nose in 36 adults undergoing sinus surgery. The goal is to see if the microscope can show differences between people with and without smell loss. This is an early-stage observation study, not a tre…

This pilot study will test whether a smartwatch can measure pain levels in 15 people with knee osteoarthritis. Participants will wear an Embrace Plus smartwatch that tracks electrodermal activity (skin signals) while reporting their pain during standard physical tests. The goal i…

This study tests whether a special light treatment can help prevent infections in people with bone-anchored prostheses (artificial limbs attached directly to the bone). Ten participants will apply a medicated cream to the skin where the metal rod comes out, then use a light devic…

This study tests a tablet-based program called Plan & Protect for teens aged 12-17 who visit rural emergency departments with suicidal thoughts or self-harm. The program helps teens and their caregivers create a personalized safety plan and reduce access to firearms and medicatio…

This study explores whether data from your smartphone can warn doctors when depression symptoms are about to return. Researchers will collect phone data from 320 adults who have been treated for depression and are currently well. They will compare this data with monthly mood ques…

This study looks at whether lidocaine, a numbing medicine, changes the signals used to monitor nerves during spine surgery. 44 adults having spine surgery will get either lidocaine or a placebo. The goal is to see if lidocaine affects the nerve monitor readings, which could help …

This small pilot study tests a simple tool called CKD Topics that helps people with advanced chronic kidney disease (stages 4-5) set the agenda for their doctor visits. The study includes 30 patients, their care partners, and clinic staff from rural areas. The goal is to see if t…

This study tests whether giving people a one-page planning guide along with their at-home colorectal cancer screening kit (FIT) helps them actually complete and return the test. About 1,600 adults aged 45-75 from primary care clinics will be randomly assigned to receive either th…