Centre Leon Berard

This trial tests whether combining an immune-boosting cream (imiquimod) with a low dose of an immunotherapy drug (nivolumab) can shrink vulvar squamous cell carcinoma tumors before surgery. About 50 women with resectable, early-to-moderate stage vulvar cancer will receive the dru…

This study explores whether equicoaching—a type of coaching with horses—can help young adults (ages 15-25) who finished cancer treatment feel more confident and reconnect with others. Ten participants will take part in the program and share their experiences through interviews an…

This study tests whether listening to a hypnotic audio recording during a 4D CT scan can reduce image artifacts (blurring or distortions) for 25 adults receiving lung cancer radiation therapy. Participants will have scans with and without the recording to compare quality. The goa…

This study aims to understand the different cell types in oral cancer and pre-cancerous mouth lesions. Researchers will analyze tissue and blood samples from 150 participants to map gene activity and cell interactions. They will also test whether a simple brush sample can replace…

This study will look at tumor samples and health records from 300 people who had surgery for rectal cancer. The goal is to find patterns in the tumor's immune environment that can predict which patients will respond well to chemotherapy or immunotherapy. This could help doctors i…

This study looks at whether a blood test can predict how well certain cancer drugs (PARP inhibitors) work in people with advanced breast, prostate, ovarian, or pancreatic cancer. Researchers will collect blood and tumor samples from 300 adults to analyze cancer cells and their DN…

This study will interview 30 children aged 6-17 who are undergoing chemotherapy for cancer, along with their parents, to understand how they deal with changes in taste, smell, and food texture. The goal is to learn what coping strategies families use at home and in the hospital t…

This study aims to create a new method to find and sort cancer cells that float in the blood of people with advanced soft tissue sarcoma. Researchers will collect blood and tumor samples from 100 adults to develop this detection technique. The goal is to better understand the dis…

This study will test a new automated blood test that measures how well a patient's T-cells (immune cells) are working. The goal is to see if the test results match how well the cancer responds to standard immunotherapy drugs like anti-PD1 or anti-CTLA4. The study will include 100…