Centre Hospitalier Universitaire Dijon

This trial tested a drug called taselisib for people with PIK3CA-related overgrowth, a rare condition where parts of the body grow too much due to a genetic mutation. The goal was to see if the drug is safe and can shrink or slow the overgrowth. The study was stopped early, so re…

This study looked at whether liraglutide, a diabetes medication, can reduce fat in the liver and improve blood fat levels in people with type 2 diabetes. It involved 127 participants and used advanced imaging and blood tests. The trial was terminated early, so results are limited…

This study tested whether a sedative called dexmedetomidine could help patients with severe septic shock respond better to blood-pressure-raising medications. Septic shock is a life-threatening condition where blood pressure drops dangerously low, and some patients stop respondin…

This study tested whether the drug levosimendan could help people with severe heart failure safely come off a heart-lung machine (ECLS). The trial planned to include 82 adults who were ready to try weaning off the machine. However, the study was terminated early, so results are l…

This study looked at whether people with Type 1 or Type 2 diabetes who have different personality types (Type A, proactive and impatient, versus Type B, calm and slow) also have different genetic markers related to inflammation and stress. Researchers collected blood samples and …

This study aimed to understand why some people taking the blood cancer drug ibrutinib develop heart problems like atrial fibrillation (irregular heartbeat) and high blood pressure. Researchers planned to follow 8 patients over time, using special heart tests to find early warning…

This study looked at 500 adults in intensive care with septic shock and severe acute kidney injury. It compared starting dialysis early (within 12 hours) versus waiting 48-60 hours to see if timing affected survival at 90 days. The study was terminated early, so no firm conclusio…

This study looked at whether a simple, non-invasive eye scan could predict how well a person's remaining kidney will work one year after having a kidney removed for cancer. Researchers examined 30 adults before and after surgery, comparing eye blood vessel patterns with kidney fu…

This study looked at how taste, food cravings, and eating behavior differ in people with type 2 diabetes compared to healthy individuals. It also examined whether the diabetes drug liraglutide changes these factors. The study involved 90 participants split into three groups: diab…

This study looked at whether tiny particles called exosomes, found in the blood of colorectal cancer patients, can be used as biomarkers to predict survival and disease progression. Researchers analyzed blood samples from 172 participants to see if the number, size, and contents …

This study aimed to confirm if a score based on age, symptom duration, initial vision, and eye scans can predict good vision recovery one year after combined cataract and epiretinal membrane surgery. The study planned to enroll 164 adults aged 40 and older. The goal was to give s…

This study looked at how mechanical ventilation affects the energy centers (mitochondria) of immune cells in the lungs and blood of patients with acute respiratory distress syndrome (ARDS). Researchers aimed to understand if these changes contribute to worse outcomes. The study w…

This study aimed to see if a mindfulness-based stress reduction program could lower stress and inflammation in people caring for someone with a severe psychiatric disorder like schizophrenia or bipolar disorder. Researchers planned to compare a group that took mindfulness classes…