Experimental drug targets rare overgrowth disorder in early trial

NCT ID NCT03290092

First seen Feb 04, 2026 · Last updated May 15, 2026 · Updated 11 times

Summary

This trial tested a drug called taselisib for people with PIK3CA-related overgrowth, a rare condition where parts of the body grow too much due to a genetic mutation. The goal was to see if the drug is safe and can shrink or slow the overgrowth. The study was stopped early, so results are limited.

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This is a summary of the original study . Summaries may miss details or leave out important information. Before applying or accepting participation, make sure you have read and understood the full study. Curemydisease.com takes no responsibility whatsoever for anything missed, misunderstood, or acted upon as a result of our summary — we know it does not capture everything.

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Contacts and locations

Locations

  • CHU Hôtel Dieu

    Nantes, 44093, France

  • CHU La Réunion - Site GHSR

    Saint-Pierre, 97448, France

  • CHU d'Angers

    Angers, 49933, France

  • CHU de Bordeaux - GH Pellegrin

    Bordeaux, 33076, France

  • CHU de Nancy

    Vandœuvre-lès-Nancy, 54511, France

  • CHU de Nancy - Hôpital de Brabois

    Vandœuvre-lès-Nancy, 54511, France

  • CHU de Nice - Hôpital l'Archet 2

    Nice, 06202, France

  • CHU de Saint-Etienne Hôpital Nord

    Saint-Priest-en-Jarez, 42270, France

  • Chu Dijon Bourgogne

    Dijon, 21000, France

  • HCL - Hôpital femme-mère-enfant

    Lyon, France

  • Hôpital Arnaud de Villeneuve

    Montpellier, 34090, France

  • Hôpital Jeanne de Flandre

    Lille, 59037, France

  • Hôpital Larrey

    Toulouse, 31059, France

  • Hôpital Necker-Enfants malades

    Paris, 75743, France

  • Hôpital Raymond Poincaré (AP-HP)

    Garches, 92380, France

  • Hôpital Saint Eloi

    Montpellier, 34295, France

  • Hôpital Sud

    Rennes, 35203, France

  • Hôpital Trousseau

    Tours, 37044, France

Conditions

Explore the condition pages connected to this study.