Centre Hospitalier Universitaire De Saint Etienne

This study tests a combination of two drugs (belantamab mafodotin and mezigdomide) in about 44 adults with multiple myeloma that came back after treatment with CAR-T cells or bispecific antibodies. The goal is to see if this new combo can control the cancer longer. Participants w…

This study compares a new software, C. Santé, to the standard sleep test (polysomnography) to see if it can accurately measure sleep quality. The software uses sensors on a bed to track breathing and heart rate without disturbing sleep. If successful, it could allow people to mon…

This study tests whether a music session led by a therapist in the evening can improve sleep and reduce agitation in people with Alzheimer's or similar memory disorders living in a special care unit. Researchers will track sleep with a wrist monitor and measure behavior changes. …

This study looks at whether adding hypnosis or relaxation sessions to standard psychological care can lower anxiety in children, teens, and young adults who have finished treatment for pediatric cancer. About 558 participants aged 7 to 25 who are in remission and have anxiety wil…

This study aims to understand why some patients with severe dry eye syndrome improve with autologous serum eye drops while others do not. Researchers will analyze the protein makeup of the eye drops from 68 participants to find differences between responders and non-responders af…

This study aims to find the best way to dose the antibiotic ceftazidime for patients in intensive care with serious infections. Many ICU patients don't get enough of the drug because their bodies process it differently. The researchers will test a personalized dosing plan to keep…

This study looks at whether doing or imagining everyday actions helps people with early Alzheimer's remember them better. Researchers will show 120 videos of daily activities to 80 older adults (some with Alzheimer's, some healthy) and test their recall. The goal is to find simpl…

This study aims to see if a personalized training recommendation strategy, powered by artificial intelligence, can help trail runners improve their performance and reduce injuries. About 1,200 competitive trail runners will be assigned to either a personalized adaptive plan, a st…

This study looks at how the brain responds to fatty food smells and images in women with anorexia nervosa. Researchers will use brain scans to compare patients with healthy women. The goal is to understand why fatty foods cause aversion, which could help improve future treatments…

This study looks at whether muscle size and quality measured by a CT scan can predict the risk of death within 3 months after leaving the ICU for patients with septic shock. Researchers will enroll 196 adults and analyze their muscle scans taken shortly after ICU admission. The g…

This study looks at whether a special MRI scan can predict if patients will develop an irregular heartbeat (atrial fibrillation) after heart bypass surgery. About 100 adults scheduled for bypass will get an MRI before surgery and wear a heart monitor for a year. The goal is to fi…

This study tests whether a 6-month sleep education program, led by an occupational health nurse, can improve sleep and health in healthcare workers who work 12-hour alternating day and night shifts. The study will involve 160 nurses and nursing assistants. The goal is to see if p…

This study looks at how to give the right amount of a clotting medicine called fibrinogen to people who have bleeding after heart surgery. The goal is to stop bleeding faster and use less medicine, which could save money and improve recovery. About 150 adults having heart surgery…