Centre Hospitalier Intercommunal Creteil

This trial tests whether a bioactive glass material can effectively fill the mastoid bone after surgery for cholesteatoma, a non-cancerous but destructive ear growth. Adults having their first cholesteatoma operation will receive the glass filler to stabilize the repair and preve…

This Phase 2 trial is testing whether a fixed dose of the hormone follitropin delta (Rekovelle) can improve ovarian stimulation for intrauterine insemination (IUI) in women with regular cycles. The goal is to promote the growth of two mature eggs per cycle to increase pregnancy c…

This study tests whether taking 150 mg of aspirin daily, starting before 20 weeks of pregnancy, can prevent serious problems like preeclampsia, poor fetal growth, placental abruption, preterm birth, and death in pregnant women with chronic high blood pressure. About 500 women wil…

This study tests whether a general practitioner's encouragement can increase the number of women who get screened for cervical cancer. Over 11,000 women aged 25-65 in France who are behind on screening will be involved. The goal is to see if a simple conversation with their famil…

This study tests whether combining aromatherapy (smelling essential oils) with hypnosis can help cancer patients feel more comfortable during uncomfortable procedures like blood draws or dressing changes. About 66 adults with cancer will be randomly assigned to receive hypnosis a…

This study compares two types of CPAP machines that help premature babies breathe. One delivers a constant flow of air, the other a variable flow. Researchers will measure the babies' diaphragm activity to see if constant flow works just as well. The study involves 20 infants bor…

This study reviews medical records of 500 Polynesian patients with bronchiectasis (widened airways) to understand why the condition is so common in French Polynesia. Researchers will look at age of onset, family history, infections, and CT scan patterns to see if a genetic cause …

This study collects exhaled breath from 240 adults—some with COPD and some without—to compare the types and amounts of bacteria present. Participants breathe through a straw into a device for 5 minutes, and a second sample is taken a year later. The goal is to understand how the …

This study looks at how doctors can improve antibiotic prescriptions for urinary tract infections (UTIs) after patients leave the emergency department. Researchers will check if adjusting antibiotics based on lab test results reduces the use of strong drugs like fluoroquinolones.…

This study aims to better understand pre-eclampsia and intrauterine growth restriction (IUGR), serious pregnancy complications affecting about 9% of pregnancies. Researchers will collect placenta, blood, and urine samples from 500 pregnant women—both with and without these condit…

This study follows 200 adult women who visit the gynecological emergency department for endometriosis or related symptoms. Researchers want to see if emergency care leads to proper follow-up, like specialist visits or imaging. The goal is to understand how well the emergency syst…

This study observes how doctors decide when to remove breathing tubes (extubation) in extremely preterm infants born before 28 weeks. Researchers will track 100 babies in the NICU, asking doctors daily why they choose to extubate or not. The goal is to understand current practice…

This study is building a national registry to collect data on people with parietal endometriosis, a condition where endometriosis tissue grows in the abdominal wall. Researchers will track those treated with either surgery or a less invasive technique called cryoablation (freezin…

This study looks at how morphine, given alone or with midazolam, works in newborns who need breathing machines in intensive care. Researchers will monitor 180 infants to find the dose that provides comfort without over-sedation. The goal is to improve pain management for these fr…

This study looks at lung tissue from 186 people having surgery for suspected lung cancer. Researchers will compare smokers with and without COPD to non-smokers, focusing on cells that help repair the lungs. The goal is to understand why some smokers develop COPD while others do n…