Bioactive glass may help seal the ear after cholesteatoma surgery
NCT ID NCT05921643
First seen Jun 27, 2026 · Last updated Jun 27, 2026
Summary
This trial tests whether a bioactive glass material can effectively fill the mastoid bone after surgery for cholesteatoma, a non-cancerous but destructive ear growth. Adults having their first cholesteatoma operation will receive the glass filler to stabilize the repair and prevent the growth from coming back. The study measures how well the mastoid fills in over six months.
What this could mean
Our plain-language read of the trial. This is informational only — not medical advice or a prediction.
- Active substance
- bioactive glass (GlassBONE or Bonalive)
- What this could lead to
- If successful, this could offer a better way to prevent cholesteatoma from coming back after surgery, reducing the need for repeat operations.
- What could go wrong
- This is a small, early-stage study with only 70 participants, and the filler's long-term safety and effectiveness are not yet proven.
This is an AI summary of the original study and may miss details. Read our disclaimer.
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Conditions
The condition(s) this trial relates to.
As listed by the trial registrant
The condition terms exactly as the trial's registrant entered them.
Contacts and locations
Locations
-
Hôpital Lyon Sud
RECRUITINGLyon, Pierre-Bénite, 69495, France