Centers For Disease Control And Prevention

This early-stage study tested a new inactivated rotavirus vaccine (CDC-9) in 50 healthy adults aged 18 to 45. The goal was to see if the vaccine is safe and triggers an immune response. Participants received three shots over several months and were monitored for side effects and …

This completed Phase 3 trial tested whether an adjuvanted flu vaccine (FLUAD Quadrivalent) triggers a stronger immune response than a standard flu vaccine (FluQuadri) in 192 healthcare workers in Lima, Peru. Participants received one dose of either vaccine, and researchers measur…

This study tested the JYNNEOS smallpox vaccine in 1,600 healthcare workers in the Democratic Republic of the Congo who are at high risk of catching mpox. The goal was to see if the vaccine can prevent mpox infection and is safe to use. Participants received the vaccine and were m…

This study tested whether the antibiotic ciprofloxacin works as well as doxycycline for treating plague, a serious bacterial infection. Only 5 people in Uganda took part, and they were randomly assigned to one of the two drugs. The goal was to see if ciprofloxacin could be a good…

This study looked at how to best dose two medicines, rifapentine and isoniazid, for children aged 0-12 with latent (hidden) tuberculosis infection. The goal was to find a dose that works as well as in adults to prevent the infection from turning into active TB. The study included…

This study tested a short video shown in HIV clinic waiting rooms to encourage patients to start and stick with their HIV medications, stay in care, and protect their partners. Over 4,000 patients from clinics serving mostly African American and Hispanic communities took part. Th…

This study looked at whether a rabies vaccine (RabAvert) can be given just under the skin instead of into a muscle. Researchers tested it in 130 adults, some who had never been vaccinated and some who had. The goal was to see if the skin shot triggers enough protection and is saf…

This study tested whether taking the tuberculosis prevention drug isoniazid for 36 months instead of the usual 6 months could better prevent TB in adults with HIV. Nearly 2,000 participants in Botswana were randomly assigned to either short or long treatment. The goal was to see …

This study evaluated a program called PALMS that uses live movement and sound to teach HIV prevention to high-risk minority male teens aged 12-18 in juvenile justice or drug treatment centers. The goal was to see if the program reduces risky sexual behaviors and encourages HIV te…

This study tested whether giving families educational materials, alcohol-based hand sanitizers, and surgical face masks could reduce the spread of colds and flu among household members. Researchers followed 2,788 people in 450 households in Northern Manhattan for 15 months. They …

This completed Phase 3 study measured how high doses of the tuberculosis drugs rifapentine and moxifloxacin move through the body in 53 adults with TB. Participants gave multiple blood samples to track drug levels. The goal was to understand the best doses to kill TB bacteria whi…