Rabies shot under the skin: could it work?

NCT ID NCT01044199

First seen Jun 27, 2026 · Last updated Jun 27, 2026

Summary

This study looked at whether a rabies vaccine (RabAvert) can be given just under the skin instead of into a muscle. Researchers tested it in 130 adults, some who had never been vaccinated and some who had. The goal was to see if the skin shot triggers enough protection and is safe. Results could lead to a simpler vaccination method.

What this could mean

Our plain-language read of the trial. This is informational only — not medical advice or a prediction.

Active substance

PCEC rabies vaccine (RabAvert)

What this could lead to

If successful, this could offer a simpler, less invasive way to protect against rabies, potentially using less vaccine per dose.

What could go wrong

This is a completed early-stage study with 130 participants, so results may not apply to everyone. The intradermal method may not be as effective as the standard shot for all people.

Disclaimer Read more

This is a summary of the original study . Summaries may miss details or leave out important information. Before applying or accepting participation, make sure you have read and understood the full study. Curemydisease.com takes no responsibility whatsoever for anything missed, misunderstood, or acted upon as a result of our summary — we know it does not capture everything.

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Conditions

The condition(s) this trial relates to.

rabies prevention target

As listed by the trial registrant

The condition terms exactly as the trial's registrant entered them.

Contacts and locations

Locations

  • CDC Occupational Clinic

    Atlanta, Georgia, 30333, United States