Boosted flu shot tested in hospital workers – could it offer better protection?
NCT ID NCT06054269
First seen Jun 25, 2026 · Last updated Jun 27, 2026 · Updated 1 time
Summary
This completed Phase 3 trial tested whether an adjuvanted flu vaccine (FLUAD Quadrivalent) triggers a stronger immune response than a standard flu vaccine (FluQuadri) in 192 healthcare workers in Lima, Peru. Participants received one dose of either vaccine, and researchers measured antibody levels at 28 days and 6 months after vaccination. The goal is to see if the adjuvanted version offers better protection against influenza.
What this could mean
Our plain-language read of the trial. This is informational only — not medical advice or a prediction.
- Active substance
- FLUAD Quadrivalent (adjuvanted influenza vaccine)
- What this could lead to
- If it works, this could show that an adjuvanted flu vaccine provides stronger or longer-lasting protection for healthcare workers than the standard vaccine.
- What could go wrong
- This is a completed Phase 3 trial with 192 participants, so results are reliable but may not apply to other populations or flu seasons. Adjuvanted vaccines can cause more local side effects like soreness.
This is an AI summary of the original study and may miss details. Read our disclaimer.
Get updates
Get notified about this study
Sign up to get updates when this study changes or when new studies for INFLUENZA are added.
By submitting, you agree to our Terms of use
Conditions
The condition(s) this trial relates to.
As listed by the trial registrant
The condition terms exactly as the trial's registrant entered them.
Contacts and locations
Locations
-
Hospital Nacional Arzobispo Loayza
Lima, 15082, Peru
-
Hospital Nacional Cayetano Heredia
Lima, 15102, Peru
More trials for these conditions
Other studies related to the condition(s) this trial covers.
- Flu vaccine showdown: which shot protects seniors best?
- Can a simple breath test catch flu in High-HIV regions?
- Can a simple mask stop the flu? 2,000 volunteers put it to the test
- Can a stronger flu shot better protect seniors?
- Flu shot showdown: Cell-Grown vs recombinant vaccine put to the test
- New mRNA vaccine aims to outsmart flu by targeting its hidden parts