Baylor Research Institute
Clinical trials sponsored by Baylor Research Institute, explained in plain language.
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Can a diabetes shot shield the heart and kidneys?
Disease control CompletedThis study tested whether a long-acting diabetes drug called exenatide can protect the heart and kidneys in people with type 2 diabetes and mild kidney problems. 57 adults received either the drug or a placebo for 38 weeks. Researchers measured blood and urine markers to see if t…
Phase: PHASE3 • Sponsor: Baylor Research Institute • Aim: Disease control
Last updated May 17, 2026 11:39 UTC
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New device plugs stroke risk in heart patients who Can't take blood thinners
Disease control CompletedThis study tested a device called the Lariat to close a small pouch in the heart (the left atrial appendage) in people with atrial fibrillation who are at risk for stroke but cannot take blood thinners. Nine participants underwent the procedure to see if it could safely and effec…
Phase: NA • Sponsor: Baylor Research Institute • Aim: Disease control
Last updated May 17, 2026 11:37 UTC
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Blood markers may spot ovarian cancer sooner
Diagnosis CompletedThis study looked for DNA markers in blood that could help detect a serious type of ovarian cancer early. Researchers compared blood and tissue samples from 10 women with and without the disease. The goal is to develop a simple blood test for earlier diagnosis.
Sponsor: Baylor Research Institute • Aim: Diagnosis
Last updated May 17, 2026 11:33 UTC
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Silver patch may shield fragile newborns from deadly infections
Prevention CompletedThis study tested whether a silver alginate dressing (Algidex) placed over central line insertion sites can prevent bloodstream infections in very low birth weight infants (500-1500 grams). Researchers compared infection rates, hospital stay length, and safety in 100 babies recei…
Phase: NA • Sponsor: Baylor Research Institute • Aim: Prevention
Last updated May 17, 2026 11:36 UTC
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Heart surgery patients may need fewer opioids with pre-incision pain block
Symptom relief CompletedThis study tested whether injecting a long-lasting pain medicine (liposomal bupivacaine) into the breastbone area before the surgeon makes the cut can reduce the need for opioid painkillers after heart surgery. 70 adults having heart surgery through the breastbone took part. The …
Phase: PHASE4 • Sponsor: Baylor Research Institute • Aim: Symptom relief
Last updated May 17, 2026 11:38 UTC
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Harmonica hacks COPD: blow away breathlessness!
Symptom relief CompletedThis study looked at whether playing the harmonica could help people with COPD. Fifteen people who had finished a lung rehab program at least six months earlier took part in a 12-week harmonica training program. The goal was to see if it could strengthen breathing muscles, reduce…
Phase: NA • Sponsor: Baylor Research Institute • Aim: Symptom relief
Last updated May 17, 2026 11:33 UTC
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15-Year Check-In: how did early fabry treatment hold up?
Knowledge-focused CompletedThis study checked on 5 adults with Fabry disease who had been taking enzyme replacement therapy (ERT) since childhood for about 15 years. Researchers measured kidney function and heart health to see how well the treatment worked over the long term. The goal was to gather informa…
Phase: NA • Sponsor: Baylor Research Institute • Aim: Knowledge-focused
Last updated May 17, 2026 11:39 UTC
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Gene hunt: could your DNA hold the key to early Alzheimer's?
Knowledge-focused CompletedThis study collected blood samples from 26 people with early-onset Alzheimer's disease and their close family members. Researchers analyzed DNA and RNA to find biological markers that could help doctors diagnose and treat the disease earlier. The goal is to better understand how …
Sponsor: Baylor Research Institute • Aim: Knowledge-focused
Last updated May 17, 2026 11:38 UTC
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New Spanish-Language screening tool tested for substance use in clinics
Knowledge-focused CompletedThis study tested a Spanish-language electronic tool called TAPS-ESP to see if it can accurately screen for tobacco, alcohol, prescription drug misuse, and illicit substance use in primary care. About 1,000 Spanish-speaking adults from a clinic took the screening, and their resul…
Phase: NA • Sponsor: Baylor Research Institute • Aim: Knowledge-focused
Last updated May 17, 2026 11:35 UTC
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Can a simple monitor transform hospital diabetes care?
Knowledge-focused CompletedThis study tested whether continuous glucose monitors (CGMs) can help track blood sugar levels in hospitalized adults with diabetes. Forty patients wore a CGM device during their hospital stay to see if it could catch dangerous highs and lows better than standard checks. The goal…
Phase: NA • Sponsor: Baylor Research Institute • Aim: Knowledge-focused
Last updated May 17, 2026 11:35 UTC
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Can a simple body scan predict heart transplant success?
Knowledge-focused CompletedThis study looked at 69 heart transplant patients to see if a special body composition scan (bioelectrical impedance spectroscopy) could help predict complications like organ rejection, kidney injury, or long hospital stays. Researchers compared the scan results with older method…
Sponsor: Baylor Research Institute • Aim: Knowledge-focused
Last updated May 17, 2026 11:32 UTC
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Heart valve fix may boost brain power in seniors
Knowledge-focused CompletedThis study looked at 81 people with mild memory problems who were getting a heart valve replacement (TAVR). Researchers tested their thinking and memory before and after the procedure using a 5-minute quiz. The goal was to see if fixing the heart valve helps improve brain functio…
Sponsor: Baylor Research Institute • Aim: Knowledge-focused
Last updated May 17, 2026 11:31 UTC
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Can a nurse or doctor report card boost diabetes care?
Knowledge-focused CompletedThis study looked at two strategies to improve diabetes care: giving doctors feedback on their performance (profiling) and having a diabetes nurse coordinate care. It included 1891 older adults with diabetes in Texas. The goal was to see if these approaches helped patients meet b…
Phase: NA • Sponsor: Baylor Research Institute • Aim: Knowledge-focused
Last updated May 17, 2026 11:30 UTC