WEANING FAILURE

This study investigates whether a specific ultrasound measurement—called maximal diaphragm thickening fraction—can accurately assess diaphragm function in patients who are on mechanical ventilation. Researchers will compare this ultrasound technique to a standard method (phrenic …

This study looks at whether repeated measurements of certain biomarkers during a spontaneous breathing trial can help predict which ICU patients will need to be re-intubated within 7 days. Researchers will follow 266 adults who have been on a ventilator for more than 48 hours and…

This study looked at 120 critically ill patients on breathing machines to see if a quick, non-invasive test called P0.1 could predict whether they would need the tube reinserted after removal. The test measures the effort to breathe in the first split second of inhalation. Resear…

This study looked at 64 adults on breathing machines to see if changes in a chest muscle (parasternal intercostal) could predict when the breathing tube could be safely removed. Researchers measured muscle thickness during breathing trials. The goal was to find a simple, non-inva…

This study looked at whether measuring tiny brain signals during a breathing test can help predict if a patient on a ventilator will successfully breathe on their own. Researchers monitored 70 intubated adults as they tried breathing without the machine. The goal is to find a sim…

This study tested two ways of taking patients off a mechanical ventilator to see which leads to more successful removals. One method used a standard breathing trial without extra pressure, while the other kept the lungs slightly inflated during the trial and removed the tube with…

This study followed 156 critically ill patients who had a tracheostomy to help them come off a breathing machine (ventilator). Researchers measured how long the weaning process took, how often patients felt short of breath or uncomfortable, and how this affected their quality of …

This study tested two different ways of using a breathing machine at night to help people with COPD get off the machine faster. Nineteen patients were randomly assigned to one of two ventilation modes during sleep. Researchers measured how long it took to wean off the ventilator …