Night ventilation showdown: which mode helps COPD patients wean faster?

NCT ID NCT01573481

Completed Knowledge-focused Sponsor: Centre Hospitalier Universitaire, Amiens Source: ClinicalTrials.gov ↗

First seen Jun 26, 2026 · Last updated Jun 26, 2026

Summary

This study tested two different ways of using a breathing machine at night to help people with COPD get off the machine faster. Nineteen patients were randomly assigned to one of two ventilation modes during sleep. Researchers measured how long it took to wean off the ventilator and how well patients slept.

What this could mean

Our plain-language read of the trial. This is informational only — not medical advice or a prediction.

Active substance: pressure support ventilation and pressure controlled ventilation
What this could lead to: If successful, this could point toward better nighttime ventilation strategies to shorten weaning time and improve sleep for COPD patients on ventilators.
What could go wrong: This is a very small, early-stage study with only 19 participants, so results may not apply broadly. The interventions are already standard modes, so no dramatic breakthrough is expected.

This is an AI summary of the original study and may miss details. Read our disclaimer.

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Conditions

The condition(s) this trial relates to.

chronic obstructive pulmonary disease

As listed by the trial registrant

The condition terms exactly as the trial's registrant entered them.

COPD EXACERBATION WEANING FAILURE

Contacts and locations

Locations

Pneumologie et Réanimation Respiratoire

Amiens, 80000, France

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