Could a Once-a-Day inhaler replace frequent treatments for COPD emergencies?
NCT ID NCT04655170
First seen Aug 03, 2026 · Last updated Aug 04, 2026 · Updated 1 time
Summary
This trial is testing whether giving long-acting bronchodilators (formoterol and revefenacin) to patients hospitalized with a COPD flare-up can improve breathing as well as or better than the standard short-acting medications (albuterol and ipratropium). The study will compare the two approaches in about 60 adults aged 40 and older who are admitted with a COPD exacerbation. The goal is to see if the long-acting option is feasible, safe, and effective in this setting, potentially simplifying treatment and improving symptom control.
What this could mean
Our plain-language read of the trial. This is informational only — not medical advice or a prediction.
- Active substance
- Long-acting bronchodilators (formoterol and revefenacin) compared with short-acting bronchodilators (albuterol and ipratropium)
- What this could lead to
- If effective, this could lead to a more convenient and effective treatment for COPD flare-ups in the hospital, potentially reducing the number of doses needed and improving patient comfort.
- What could go wrong
- This is a small, early-stage trial (60 patients) that may not show a clear benefit. Long-acting bronchodilators may not be as effective or safe as the standard short-acting drugs in acute hospital settings.
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As listed by the trial registrant
The condition terms exactly as the trial's registrant entered them.
Contacts and locations
Locations
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University of Tennessee Medical Center
Knoxville, Tennessee, 37920-6999, United States
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